Cutaneous horn is a horn-like keratotic lesion, which commonly occurs on the head and face, over a wide range of benign or malignant skin lesions. Callosity is a hyperkeratotic plaque produced by intermittent or continuous pressure on the skin. Lateral aspects of the ankles (Lateral malleoli) are frequently involved. We report a rare case of cutaneous horn developed on ankle callosity.

We have investigated the effect of giving two 25 mg doses of dry surfactant powder to the airways of 10 preterm babies with severe idiopathic respiratory distress syndrome requiring intermittent positive pressure ventilation. No useful change in static total compliance or blood gases was seen. We conclude that dry surfactant powder does not have a role in the management of severe idiopathic res...

I read with great interest the article by Raman et al 1 in a recent issue of CHEST (February 2015) that evaluated the pressure tolerance of esophagectomy anastomosis ex vivo and in vivo in a pig model in comparison with esophageal pressure during noninvasive positivepressure ventilation (NPPV). Th e authors showed that anastomosis can tolerate higher pressures than those transmitted to the esop...

This study was conducted to determine whether small doses of salbutamol solution, aerosolised and delivered by intermittent positive-pressure breathing (IPPB), would be as effective as the 5 to 10 mg dose usually recommended for inhalational use. In nine asthmatic subjects we found that there was no significant difference between the peak bronchodilator effect of 1.0, 2.5, and 5.0 mg of salbuta...

Negative pressure ventilation, the intermittent application of subatmospheric pressure around the chest and abdomen to assist breathing, is founded on sound physiological principles. As long as atmospheric pressure is maintained at the mouth and nose (and the upper airway remains patent), the negative peri-thoracic and-abdominal pressure increases the transpul-monary gradient, expanding the che...