Several studies suggest that patient self-management (PSM) may improve the quality of oral anticoagulation therapy as measured by time spent within the international normalised ratio (INR) target range. We performed a prospective randomised control trial to determine whether the improvement in quality of treatment afforded by PSM is greater than that achieved by patient self-testing (PST) alone...

MATERIAL AND METHODS: Affiliation search of the Scopus database was performed on November 23, 2014 in order to identify published papers from the Ss Cyril and Methodius University of Skopje (UC&M), Republic of Macedonia. A total number of 3960 articles (3055 articles from UC&M, 861 articles from Faculty of Medicine, UC&M, and 144 articles from Faculty of Pharmacy, UC&M) were selected for analys...

In red-NIR reflectance space, the Modified Soil Adjusted Vegetation Index (MSAVI) isolines, representing similar vegetation biophysical quantities, are neither convergent to a point nor parallel to each other. Consequently, the treatment of the MSAVI isolines is distinctly different from those of other vegetation index isolines, such as the normalized difference vegetation index (NDVI), the per...

Advances in preclinical SMA research have identified several candidate treatments. Early clinical trials evaluating these medications are underway or in the planning stage. At the NINDS Workshop on SMA in September 2004 in Washington DC, discussions started within the international SMA community to identify features that should be common to SMA clinical trials [1]. Having a set of design featur...

The establishment of a total maximum daily load (TMDL) is part of management process that results in the institution of watershed-based controls of otherwise unregulated sources of pollution. In California (USA), the implementation of a TMDL is driven forward in a process where watershed stakeholders are expected to cooperate on actions needed to improve ecosystem health. In the TMDL process, m...

BACKGROUND Observed differences between results obtained from comparison of instruments used to measure international normalized ratio (INR) have been higher than expected from the imprecision of the instruments. In this study the variation of these differences was divided into subcomponents, and each of the subcomponents was estimated. METHODS Blood samples were collected at 4 different pati...

The effectiveness of the Birmingham model of primary care oral anticoagulation management has previously been demonstrated within a randomised controlled trial. The aim of this study was to assess the effectiveness of the Birmingham model in routine care. All patients from 12 primary care centres attending either practice-based or hospital-based anticoagulation clinics were retrospectively foll...