Hyperlipidemia is a cardiovascular risk factor. In patients with idiopathic dilated cardiomyopathy (IDC), prognostic roles of endogenous lipoproteins are not fully clarified. It has been known that there is a direct relationship between the levels of cytokines (tumor necrosis factor-alpha [TNF-alpha] and interleukin-6 [IL-6]) and deteriorating functional classes of heart failure and mortality. ...

The distinction between tubular carcinomas (TC) and invasive well-differentiated (grade 1) ductal carcinoma (IDC) is important given treatment and prognostic differences. Studies have described a strong association between flat epithelial atypia (FEA) and TC. The incidence of FEA associated with grade 1 IDC is not well established. The aim of the present study was to assess morphology and intra...

Today, the Internet of Things (IoT) is increasingly flourishing with establishing ubiquitous connections between smart devices and objects, by 2020, there will be a total 30 billion connected things reported IDC. The unprecedented data explosion provides immense opportunities for valuable information mining. At same time, it also floods infrastructure tremendous values necessarily handles propo...

Cloud Data Scaling Total data produced per year surpassed one zettabyte in 2010 and continues to more than double every two years.3 To put this in perspective, about two zettabytes (ZB) of digital universe will be created (per IDC) in 2011 is two million terabytes, or over one million new 3.5" SATA disks with two terabyte (TB) capacities. At the same time, not only is total data stored growing ...

In this paper, we consider construct high order semi-implicit integrators using integral deferred correction (IDC) to solve stiff initial value problems. The general framework for the construction of these semi-implicit methods uses uniformly distributed nodes and additive RungeKutta (ARK) integrators as base schemes inside an IDC framework, which we refer to as IDC-ARK methods. We establish un...

Hormone receptor-positive (HR+), HER2-negative (HER2-) breast cancer (BC) accounts for around 65% of all BCs. Invasive lobular and ductal carcinoma (ILC, IDC) show distinct histology clinical presentation. In this study, our goal is to exploit morphological differences between IDC ILC by combining artificial intelligence spatial transcriptomics (ST) characterize intra-tumor heterogeneity. We an...

Idiopathic dilated cardiomyopathy (IDC) is a common clinical problem in Africa. To determine if there is a defect of immune regulation in patients with IDC, the percentage of total T-cells (OKT3 positive), helper/inducer cells (OKT4 positive) and suppressor/cytotoxic cells (OKT8 positive) were measured using monoclonal antibodies in 20 patients with IDC and in 20 age-matched normal control subj...

The synthesis of a variety of 2-oxindoles bearing an all-carbon quaternary center at the pseudo benzylic position has been achieved via a 'transition-metal-free' intramolecular dehydrogenative coupling (IDC). The construction of 2-oxindole moieties was carried out through formation of carbon-carbon bonds using KOt-Bu-catalyzed one pot C-alkylation of β-N-arylamido esters with alkyl halides foll...

Reciprocal interactions between cancers and the surrounding microenvironment have an important role in tumour evolution. In this study, our data suggested that through thrombospondin 1 (TSP1), tumour-associated microvessel provides a dormant niche to sustain inactive status of breast invasive ductal carcinoma (IDC) cells. TSP1 levels in the tumour stroma were negatively correlated with vascular...

BACKGROUND To investigate the clinicopathological characteristics and the survival outcomes of invasive lobular carcinoma (ILC) patients compared to invasive ductal carcinoma (IDC) patients according to their molecular subtype. METHODS We compared the clinicopathological characteristics, breast cancer-specific survival (BCSS) and overall survival (OS) between patients with IDC (n = 14,547) an...