Recent advances in understanding the complex biology of the microenvironment that underlies tumor invasion and migration have revealed novel and promising therapeutic targets. Pharmacological blockade of intra- and extracellular signaling events that regulate migration and survival of multiple cell types may disrupt the host-tumor conspiracy that allows escape from normal developmental regulation.

OBJECTIVES To examine regional and temporal trends in migration among patients receiving HIV treatment in British Columbia (BC). METHODS Patients initiating antiretroviral therapy in BC between January 1993 and November 2004 were followed until November 2005. Migration was calculated as the cumulative number of times a patient's residential address changed during their course of treatment. An...

In Thailand, gross provincial product is highly unequal while household income exhibits moderate between-province inequality. This paper introduces a dynamic model to analyze the link between migration and cross-province inequality. The wage differential drives rural-to-urban migration and in turn the wage rate at the destination is affected by total amount of migrant labor supply. Migration ge...

There are wide reports of advances in the timing of spring migration of birds over time and in relation to rising temperatures, though phenological responses vary substantially within and among species. An understanding of the ecological, life-history and geographic variables that predict this intra- and interspecific variation can guide our projections of how populations and species are likely...

Dendritic cells (DCs) are essential in T cell-mediated destruction of insulin-producing beta cells in the islets of Langerhans in type 1 diabetes. In this study, we investigated T cell induction of intra-islet DC maturation during the progression of the disease in both autoimmune-prone NOD and resistant C57BL/6 mice. We demonstrated steady-state capture and retention of unprocessed beta cell-de...

Internal migration plays a crucial role in influencing real changes local area population size and facilitating the efficient functions of regional national labor market housing. This study is conducted to investigate elements at household level others provincial level, which have impacts on decision personal migration. We used database living standards surveys 2010, 2012, 2014 Vietnam. Logit m...