نتایج جستجو برای: intraepithelial lymphocytes
تعداد نتایج: 84229 فیلتر نتایج به سال:
The cadherins are a family of homophilic adhesion molecules that play a vital role in the formation of cellular junctions and in tissue morphogenesis. Members of the integrin family are also involved in cell to cell adhesion, but bind heterophilically to immunoglobulin superfamily molecules such as intracellular adhesion molecule (ICAM)-1, vascular cell adhesion molecule (VCAM)-1, or mucosal ad...
The significance of tumor-infiltrating lymphocytes (TIL) has attracted much attention in relation to the prognosis of patients. We herein examined the activation status of the TILs in relation to the tumor microenvironment. By using frozen sections of human early-stage tongue cancers (n = 22), the TILs in the cancer nests and those in the cancer stroma were compared for the expression of PD-1, ...
Background IL-15 is involved in the development and homeostasis of CD8 lymphocytes, NK and iNKT cells, and intraepithelial lymphocytes. It also promotes migration, proliferation and survival of mast cells. Its receptor on lymphocytes is a heterotrimeric complex which shares the IL2-Rb and common gamma ( gc ) chains. IL-15-mediated signaling in mast cells might make use of an alternative recepto...
The intestinal component of a graft-versus-host reaction (GvHR) provides a useful experimental model to elucidate the pathogenesis of clinical enteropathies which cause villus atrophy and crypt hyperplasia and which are associated with a local immune response. One to three days after induction of GvHR in heavily irradiated (CBAxBALB/c)F1 mice, a proliferative form of enteropathy developed. Comp...
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