Background and Aims: Inclusion body hepatitis (IBH) is one of the most important reemerging diseases in many countries with intensive poultry industries. In Iran, the etiological agent of IBH (fowl adenovirus) has not been yet confirmed. The aim of this study was the molecular detection and identification of fowl adenovirus involving IBH in chicken flocks in Iran. Materials and Methods: Polymer...

A male pigeon (Columba livia) dead with no clinical signs was investigated of having hepatitis. Light microscopy revealed intranuclear inclusion bodies, that ultrastructurally were shown to be herpesvirus-like particles. The particles were also found in the cytoplasm. These findings are consistent with previous reports of the disease in the pigeon. This is the first time the disease has been re...

Glomerular development of the kidney was studied in newborn rats by electron microscopy. Four different stages of glomerular development were defined: vesicle fonnation, S-shaped body stage, capillary loop fonnation, and glomerular maturation. In the fust stage, the mesenchymal cells form a spheroid mass. This is followed by the S-shaped body stage in which clefts appear in the mass. Afte...

background: the refolding of proteins from inclusion bodies is affected by several factors, including solubilization of inclusion bodies by denaturants, removal of the denaturant, and assistance of refolding by small molecule additives. objectives: the purpose of this study was optimization of recombinant human interferon-b purification in order to achieve higher efficiency, yield, and a produc...

The obscrved semidiurnal wind in the troposphere at five niid-latmit,ude stations shows a, phase lead over the wind dcduccd from frictionlcss theory, and a smaller amplitude, espccially near the earth’s surface, than the theoretical value. By making use of the obscrved fact that the tidal pressure-dependent (frictionless) wind changes much less rapidly with height than does the observed wiiid i...

The adrenal gland is the most commonly involved endocrine organ in autopsy studies of patients who die of Acquired Immunodeficiency Syndrome (AIDS) (Welch 1984). The most common finding at autopsy is the presence of intranuclear or intracytoplasmic inclusion bodies in enlarged adrenal cells, indicative of Cytomegalovirus (CMV) adrenalitis (Eledrisi & Verghese 2001). Despite the frequent involve...

The kidneys from six immunodeficient mice examined by Cerberus Sciences and the Animal Resources Centre, displayed karyomegaly with pale eosinophilic, intranuclear inclusions upon histopathological examination. Electron microscopy performed on kidney tissue from 5/6 mice demonstrated margination of the chromatin in large nuclei. Laboratory tests were used to detect nucleic acid of papillomaviru...

Fabry's disease is a rare inherited metabolic disorder caused by a deficiency in the enzyme alpha-galactosidase A. It can affect almost every organ, including the lungs. Confirmation of lung involvement has depended on invasive bronchial biopsy specimens or brushings to confirm the presence of typical lamellar inclusion bodies within bronchial epithelial cells. We report a patient with known Fa...

The hypothalamus of adult male mice was investigated with the electron microscope. In all hypothalamic nuclei examined the nerve cells frequently contained nucleolus-like inclusion bodies in the cytoplasm. These inclusion bodies appeared to be composed of the same constituent particles as those of the intranuclear nucleolus. This permits consideration of their probable nuclear origin. The acces...