Inula grantioides (Boiss.) syn. /. cutchica Clarke is found in South West Pakistan, Karachi (Sindh), Kutch, Indus delta and Baluchistan. The plant is recommended for the treatment of asthma. This plant has not been subjected to chemical investiga­ tion so far. In the present paper we wish to report the isolation of two new flavones, grantionin 1 and grantioidinin 2 along with pluchidione 3, a k...

Five new dimeric sesquiterpene lactones, neojaponicone A (1) and japonicones M-P (2-5) were isolated from the aerial part of Inula japonica. Neojaponicone A (1) has an unprecedented carbon skeleton with an unusual valerolactone system formed between a guaianolide and an eudesmane. The structure and absolute configuration of 1 were established by extensive analysis of spectroscopic data and comp...

The title compound, C(14)H(24)O(2), was synthesized from ilicic acid, which was isolated from the aerial part of Inula Viscosa- (L) Aiton [or Dittrichia Viscosa- (L) Greuter]. The mol-ecule contains two fused six-membered rings, which both display a chair conformation. In the crystal, mol-ecules are linked into chains propagating along the b axis by inter-molecular O-H⋯O hydrogen bonds.

The title compound, C(21)H(26)O, was semisynthesized from isocostic acid, isolated from the aerial part of Inula Viscosa- (L) Aiton [or Dittrichia Viscosa- (L) Greuter]. The cyclo-hexene ring has a half-chair conformation, whereas the cyclo-hexane ring displays a chair conformation.

Aerial parts of Inula montana were investigated for its sesquiterpenoid composition. Five sesquiterpene lactones, isoinuviscolide, gaillardin, 1beta-hydroxy-3beta-acetoxy-eudesm-4(15), 11(13)-dien-12-8beta-olide, pulchellin-C and pulchellin-E were identified for the first time in this plant. One of them, 1beta-hydroxy-3beta-acetoxy-eudesm-4(15),11(13)-dien-1 2-8beta-olide, is a novel natural pr...