A series of diethylmethyl(2-methoxyethyl)ammonium (DEME)-based ionic liquids were prepared using bis(perfluoroalkanesulfonyl)amide (C(n)F(2n+1)SO(2))(2)N anions with different perfluoroalkyl chain lengths (n = 0, 1, 2, 3, and 4), and the influence of the structural variation on their thermal, ion-diffusive (ionic conductivity and viscosity), ion-concentration (molar concentration and ion associ...

The conductance o f N al in acetonitrile-water mixtures was measured at 25.000 ± 0.001 °C for the whole com position range o f the mixed solvent, the salt molarity ranging from 5 • 10“ 5 to 1 • 10-2 . Using the Fuoss-Hsia equation with the Femandez-Prini parameters, the association constants were computed for several values o f the ion-ion distances. The influence o f the mixed solvent composit...

The association between monovalent salts and neutral lipid bilayers is known to influence global bilayer structural properties such as headgroup conformational fluctuations and the dipole potential. The local influence of the ions, however, has been unknown due to limited structural resolution of experimental methods. Molecular dynamics simulations are used here to elucidate local structural re...

Chemical studies have been carried out on the interaction of DNA with uranyl salts. The effect of variations in pH, salt concentration, and structural integrity of the DNA on the stoichiometry of the salt-substrate complex have been investigated. At pH 3.5 DNA interacts with uranyl ions in low concentration yielding a substrate metal ion complex with a UO(2) (++)/P mole ratio of about (1/2) and...

Molecular dynamics simulations of supercritical electrolyte solutions with three different ion–water models are performed to study the anion–cation potential of mean force of an infinitely dilute aqueous NaCl solution in the vicinity of the solvent’s critical point. The association constant for the ion pair Na/Cl and the constant of equilibrium between the solvent-separated and the contact ion ...

This work presents a rigorous continuum model describing the transport of ions and associated ion pairs in solid polymer electrolytes subjected to small amplitude alternating current ~ac! excitation. The model treats ion association as a reversible reaction among ions and ion pairs. Dimensionless governing equations are developed from component mass balances, flux equations based on dilute solu...

Recent studies of AF have identified mutations in a series of ion channels; however, these mutations appear to be relatively rare causes of AF. A genome-wide association study has identified novel variants on chromosome 4 associated with AF, although the mechanism of action for these variants remains unknown. Ultimately, a greater understanding of the genetics of AF should yield insights into n...

Oligomers of homomeric voltage-gated potassium channels associate early in biogenesis as the nascent proteins emerge from the polysome. Less is known about how proteins emerging from different polysomes associate to form hetero-oligomeric channels. Here, we report that alternate mRNA transcripts encoding human ether-à-go-go-related gene (hERG) 1a and 1b subunits, which assemble to produce ion c...