background: curcumin as a yellow natural compound extracted from turmeric root is known it as an antibacterial agent. one of the nanoparticles ability is to decrease the defects of usual drug delivery systems. chitosan is a low toxic, biodegradable, biocompatible and safe polymer which is used in production of nanoparticles. nanoparticles like chitosan-tripolyphosphate (tpp) are able to increas...

Objective: The aim of the present study is to develop pH-responsive polymeric microbeads for controlled release doxorubicin. Methods: Doxorubicin-encapsulated were developed by a simple ionotropic gelation method using sodium alginate, gum ghatti, and montmorillonite (MMT). In this work, we investigate positive benefits MMT mineral as drug carrier DOX. X-ray diffraction (XRD), Fourier transform...

The aim of the present study was to evaluate physical and antioxidant properties chocolate alginate beads containing Moringa oleifera leaf extract (MLE) produced with ecofriendly solvent extraction technology (Deep Eutectic Solvents). concentration MLE incorporated 0, 2, 4, 6% w / , hardening time for iono...

Conventional antibiotics are facing significant microbial resistance, which has recently reached previously unnoticed critical levels. As a result of this situation, large proportion antimicrobial agents currently used in the clinic have significantly reduced therapeutic potential. Antimicrobial peptides (AMPs) may offer medical community an alternative strategy to traditional fight against res...

Background: Curcumin as a yellow natural compound extracted from turmeric root is known it as an antibacterial agent. One of the nanoparticles ability is to decrease the defects of usual drug delivery systems. Chitosan is a low toxic, biodegradable, biocompatible and safe polymer which is used in production of nanoparticles. Nanoparticles like chitosan-tripolyphosphate (TPP) are able to increas...

Objective(s): Currently, the development of nanoparticles for the stabilization and targeted delivery of cardiac drugs has gained significance. The present study aimed to develop nontoxic nanoparticles based on chitosan-hyaluronic acid (HA), encapsulate dinitrosyl iron complexes (DNICs, donors NO) into the nanoparticles to increase the stability and effectiveness of their action, and assess the...

The clinical effectiveness of tissue conditioners is influenced by their gelation characteristics and viscoelastic properties after gelation. The purpose of this study was to evaluate the effect of addition of ethyl alcohol (EtOH) on these properties, and to compare the effect of EtOH with that of the powder/liquid (P/L) ratio. Three tissue conditioners were used in this study. The gelation tim...

Background: Use of biodegradable natural materials as pharmaceutical excipients is increasing. In this study, Naproxen loaded microbeads were produced, using gums obtained from Cedrela odorata and Irvingia gabonensisObjective: Aim to evaluate physicochemical properties the determining release formulations.Materials Methods: gum (CG) (IG) extracted gabonensis respectively, characterized by visco...