Ribavirin (1-beta-D-ribofuranosyl-1,2,4-triazole-3-carboxamide) at concentrations of 10 microgram/ml or more, inhibited the replication of infectious pancreatic necrosis virus (IPNV) in both Chinook salmon embryo (CHSE-214) and rainbow trout gonad (RTG-2) cells. The drug was most effective when added just before or within 8 h p.i. Incorporation studies with radioactive precursors demonstrated t...

During February 2000, two trout farms, situated in NW Greece, reported unusually high losses of hatchery reared rainbow trout fry and fingerlings. Live fish and chilled samples of diseased whole fish were delivered to a veterinary laboratory in Athens for diagnostic investigation. Infections with the fungus Ichthyophonus hoferi as well as the Gram negative bacterium Aeromonas hydrophila were di...

The effects of Corexit 9500, a dispersant used to clean up oil spills, on invertebrates, lower vertebrates, birds, and human health have been examined, but there is a significant lack of study of the effect of this dispersant on aquatic viruses. In this study, the effects of Corexit 9500 on four aquatic viruses of differing structural composition were examined. Corexit 9500 reduced the titer of...