Noteworthy heterogeneity exists in the rare diseases associated with childhood glaucoma. Primary congenital glaucoma is mostly sporadic; however, 10% to 40% of cases are familial. CYP1B1 gene mutations seem to account for 87% of familial cases and 27% of sporadic cases. Childhood glaucoma is classified in primary and secondary congenital glaucoma, further divided as glaucoma arising in dysgenes...

The iridocorneal angle and inner layers of the trabecular meshwork in human fetal eyes were studied by scanning electron microscopy. Tissue from 32 eyes of 17 fetuses with a gestational age from 12 to 22 weeks were investigated in order to determine the morphological changes in the cellular lining of the anterior chamber angle recess during development. The findings indicate that, although hexa...

Abstract Descemet Membrane Endothelial Keratoplasty (DMEK) has become a first-line treatment in corneal endothelial diseases owing to its exceptional clinical outcomes and low complication rates. Thanks refractive predictability the ability reshape superficial cornea, DMEK is now also considered for managing cases with decompensation following previous procedures. This article reviews of three ...

The purpose of this report is to provide a comprehensive account an exceptional case involving the presentation congenital rubella syndrome (CRS) in newborn. Furthermore, it aims document successful regression CRS through medical treatment alone. We present five-day-old infant who was referred our facility as case. patient presented with bilateral white corneal opacity, which observed shortly a...

Endothelial dysfunction plays a crucial role in severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection and has recently been proposed to be connected with thrombosis, hyper-inflammation, cytokine storm syndrome, immune cell recruitment, platelet aggregation, vasoconstriction endothelial apoptosis. Importantly, certain mediators pro-inflammatory cytokines such as galectin (Gal) 1...

Optical coherence tomography is a high resolution, rapid, and noninvasive diagnostic tool for angle closure glaucoma. In this paper, we present a new strategy for the classification of the angle closure glaucoma using morphological shape analysis of the iridocorneal angle. The angle structure configuration is quantified by the following six features: (1) mean of the continuous measurement of th...

The article contains the analysis of results concerning investigation adipocytokines content and endothelial dysfunction in 97 patients with irritable bowel syndrome associated obesity. blood serum was examined for (leptin, adiponectin, resistin), stable nitrogen monoxide metabolites (nitrites/nitrates), endothelin-1, intercellular adhesion molecule 1 (ICAM-1), number circulating cells (CEC). P...

Axenfeld-Rieger syndrome (ARS) and iridogoniodysgenesis syndrome (IGDS) are clinically related autosomal dominant disorders which affect the anterior segment of the eye as well as non-ocular structures. ARS patients present with iris hypoplasia, a prominent Schwalbe line, adhesions between the iris stroma and the iridocorneal angle and increased intraocular pressure. IGDS is characterized by ir...