It is reasonable to consider the technical possibility and oncological feasibility of local tumor destruction in patients with locally advanced pancreatic cancer (PCa). Irreversible electroporation (IRE) a non-thermal method ablation, which uses energy high-voltage ultrashort electric fields localized between electrodes create nanopores cellular wall following death. The zone impact can be accu...

Emerging studies have showed irreversible electroporation (IRE) focused on pancreatic cancer (PC). However, the effects of IRE treatment immune response PC remain unknown. Moreover, there are few therapeutic effect combining with immunotherapy PC. Thus, we review recent advances in our understanding alone and its working towards PC, discussing potential opportunities for exploring future strate...

Sterilization using high-intensity electric fields is detrimental to health if safety inadequate, so it necessary study the possibility of sterilization low-intensity fields. This aims determine lowest field intensity and treatment time deactivate bacteria that make up biofilms explain mechanism inactivation. The samples were from Pseudomonas aeruginosa Staphylococcus epidermidis grown on cathe...

BACKGROUND Irreversible electroporation (IRE) is a tissue ablation method, which relies on the phenomenon of electroporation. When cells are exposed to a sufficiently electric field, the plasma membrane is disrupted and cells undergo an apoptotic or necrotic cell death. Although heating effects are known IRE is considered as non-thermal ablation technique and is currently applied to treat tumor...

Electroporation is believed to be a nonthermal phenomenon at the membrane level. However, the effects of associated processes, such as Joule heating, should be considered. Because electroporation of skin, specifically the stratum corneum (SC), occurs at highly localized sites, the heating is expected to conform locally to the sites of electroporation. Significant localized heating was found to ...

We report in a 65-year-old man hepatocellular carcinoma adjacent to a transjugular intrahepatic portosystemic shunt stent-graft which was successfully treated with irreversible electroporation (IRE). IRE is a new non-thermal tissue ablation technique which uses electrical pulses to induce cell necrosis by irreversible membrane poration. IRE proved to be more advantageous in the ablation of peri...