background: inflammation and infectious agents such as chlamydia pneumoniae have been associated with cardiovascular disease. objective: to evaluate the serum high sensitivity c - reactive protein (hs-crp) and antibodies against chlamydia pneumoniae and chlamydial heat shock protein-60 (cp-hsp60) in patients with ischemic heart disease (ihd). methods: 62 patients with ihd having either acute my...

Ischemic and nonischemic cardiomyopathies are associated with significant morbidity and mortality in industrialized countries. Cardiomyopathies of primary origin, and more specifically the dilated form of the disease, have been associated with a number of gene defects in cytoskeletal, membrane, and sarcomeric proteins. Cardiomyopathies of secondary origin such as ischemic cardiomyopathy remain ...

dmm.biologists.org 344 The clinical problem Ischemic and non-ischemic cardiomyopathies eventually lead to left ventricular dysfunction and heart failure. Heart failure impedes quality of life, decreases life expectancy and increases medical costs dramatically, and thus constitutes a major health problem (McMurray and Pfeffer, 2005). As the population ages, the prevalence of heart failure will i...

Cardiomyopathies are a group of diseases characterized by the structural and functional abnormalities heart muscles in absence other illnesses that might be responsible for observed myocardial anomaly. Hypertrophic dilated cardiomyopathies most prevalent types. Rare types include restrictive cardiomyopathy with arrhythmia. Dilated has documented prevalence 36 cases per 100,000 population Europe...

Ischemic heart failure (IHF), heart failure secondary to myocardial infarction, is the number one killer in the US. Despite all the major advances in cardiac interventions, its relevance is on the rise. There is an urgent need for an effective alternative therapy. Stem cells have the potential to ameliorate many chronic illnesses such as IHF. Like any new therapy, several unanswered questions n...

Heart failure is a common clinical condition associated with high morbidity and mortality rate despite significant improvements in pharmacotherapy and implementation of medical procedures. Patients with heart failure are at an increased risk of developing arterial and venous thrombosis, which contribute to the high rate of adverse events and fatal outcomes. Many heart failure patients routinely...

the incidence and prevalence of obesity are fast increasing worldwide. various indices have been used to measure and assess obesity. the body mass index (bmi) is the most common and practical of these indices. overweight and obesity exert considerable adverse effects on the cardiovascular system. these effects are mediated through various neurohormonal and cytokine pathways, most of which are i...

objectives: anemia is prevalent in heart failures and is an independent risk factor for adverse clinical outcomes in patients with chf. the aim of the present study was to determine the prevalence of anemia in elderly with systolic heart failure hospitalized in alborz hospital of karaj in 2009. methods & materials: this is a descriptive retrospective study that reviewed 154 medical records of e...

OBJECTIVES We sought to determine the relative impact of diabetes mellitus on prognosis in ischemic compared with nonischemic cardiomyopathy. BACKGROUND Ischemic myocardium is characterized by increased reliance on aerobic and anaerobic glycolysis. Because glucose utilization by cardiomyocytes is an insulin-mediated process, we hypothesized that diabetes would have a more adverse impact on mo...

The article presents data on heart damage in patients with rheumatoid arthritis (RA), features of the development ischemic and non-ischemic disease a significant increase risk adverse cardiovascular events. Patients RA are characterized by an increased developing myocardial infarction, failure, rhythm disturbances, sudden cardiac death, general death. possibility fairly rapid dysfunction from m...