نتایج جستجو برای: isoforms

تعداد نتایج: 31177  

Journal: :Israel Journal of Plant Sciences 2021

Abstract Metal pollution represents a serious issue for sustainable agronomy and food safety. Activation of plants’ protective mechanisms has been shown to depend on the extent soil contamination with metal, but reports dose-dependent responses (especially extreme concentrations) are rather rare. In this research we exposed soybean ( Glycine max L.) roots at very early stage scale cadmium conce...

Journal: :FASEB bioAdvances 2023

Abnormal myelination underlies the pathology of white matter diseases such as preterm injury and multiple sclerosis. Osteopontin (OPN) has been suggested to play a role in myelination. Murine OPN mRNA is translated into secreted isoform (sOPN) or an intracellular (iOPN). Whether there isoform-specific involvement unknown. Here we generated mouse models that either lacked both isoforms all cells...

Journal: :Plant physiology 1996
T Mitsui J Yamaguchi T Akazawa

We have identified, purified, and characterized 10 alpha-amylase isoforms from suspension-cultured rice (Oryza sativa L.) cells having different isoelectric point values. They had distinguishable optimum temperatures for enzymatic activity and molecular sizes. The results of immunoblotting indicated that polyclonal anti-A + B antibodies bound well to isoforms A, B, Y, and Z but weakly or not at...

2010
Yanhua Bai Misa Nakamura Gengyin Zhou Yaqiong Li Zhiyan Liu Takashi Ozaki Ichiro Mori Kennichi Kakudo

Periostin is an extracellular matrix protein. Five isoforms of human periostin cDNA have been reported, but the expression of periostin isoforms in the human thyroid tissue is by far unknown. A group of primer sets were designed to amplify the full length of cDNA sequence of periostin. Using human thyroid carcinoma and their paired non-neoplastic tissues together with anaplastic thyroid carcino...

Journal: :American journal of physiology. Heart and circulatory physiology 2001
K Trombitás Y Wu D Labeit S Labeit H Granzier

Titin, the third myofilament type of cardiac muscle, contains a molecular spring segment that gives rise to passive forces in stretched myocardium and to restoring forces in shortened myocardium. We studied cardiac titin isoforms (N2B and N2BA) that contain length variants of the molecular spring segment. We investigated how coexpression of isoforms takes place at the level of the half-sarcomer...

Journal: :Journal of Investigative Dermatology 2023

Epidermal stability depends on keratin intermediate filaments, which form a trans-cellular mechanical scaffold. During epidermal remodeling, filament composition shifts, with increased expression of five wound-associated isoforms. However, the function keratins during remodeling remains unclear. Identifying isoform-specific functions has been challenging, since depleting individual compromises ...

Journal: :BMC Bioinformatics 2021

Abstract Background Next generation sequencing has allowed the discovery of miRNA isoforms, termed isomiRs. Some isomiRs are derived from imprecise processing pre-miRNA precursors, leading to length variants. Additional variability is introduced by non-templated addition bases at ends or editing internal bases, resulting in base differences relative template DNA sequence. We hypothesized that s...

Journal: :The Journal of endocrinology 1999
G Kovalevskaya S Birken T Kakuma J F O'Connor

Human chorionic gonadotropin (hCG) exhibits molecular heterogeneity in both its protein and carbohydrate moieties. This communication describes changes in hCG isoforms detected directly in clinical samples. These isoforms, quantified in blood or urine specimens, show a progression of change throughout normal pregnancy. Early pregnancy produces a type of hCG that resembles, in terms of immunorea...

Journal: :Molecular pharmacology 2006
Remko A Bakker Adrian Flores Lozada André van Marle Fiona C Shenton Guillaume Drutel Kaj Karlstedt Marcel Hoffmann Minnamaija Lintunen Yumiko Yamamoto Richard M van Rijn Paul L Chazot Pertti Panula Rob Leurs

We described previously the cDNA cloning of three functional rat histamine H3 receptor (rH3R) isoforms as well as the differential brain expression patterns of their corresponding mRNAs and signaling properties of the resulting rH3A, rH3B, and rH3C receptor isoforms (Mol Pharmacol 59:1-8). In the current report, we describe the cDNA cloning, mRNA localization in the rat central nervous system, ...

Journal: :The Journal of biological chemistry 1999
V S Reddy F Safadi R E Zielinski A S Reddy

In Arabidopsis and other plants there are multiple calmodulin isoforms. However, the role of these isoforms in regulating the activity of target proteins is obscure. Here, we analyzed the interaction between a kinesin-like calmodulin-binding motor protein (Reddy, A. S. N., Safadi, F., Narasimhulu, S. B., Golovkin, M., and Hu, X. (1996) J. Biol. Chem. 271, 7052-7060) and three calmodulin isoform...

نمودار تعداد نتایج جستجو در هر سال

با کلیک روی نمودار نتایج را به سال انتشار فیلتر کنید