OBJECTIVE To investigate the extent to which children with ADHD in various medication statuses (i.e., medication naïve, pure stimulant, stimulant plus another medication, nonstimulants) varied on cognitive or academic, behavioral, and social functioning during a psychoeducational assessment battery. METHOD Participants for this study consisted of 66 children (20 girls) with a Diagnostic and S...

Introduction Whether melancholia is a distinct syndrome has long been debated. One aspect of valid whether it allows for determination prognosis. The aim this study to investigate the course melancholic depression versus non-melancholic with focus on: (i) time and probability recovery from first depressive episode, (ii) risk recurrence, (iii) rate (iv) or antidepressant medication, (v) suicide ...

Understanding the strengths and weaknesses of a technology in the context of the distributed system in which it is working is critical to assessing and improving the performance of that system. Taking a systems approach requires knowledge about how all agents in a system work together to achieve the goals of that system. With these aims, the alerting mechanism of infusion pumps containing Dose-...

BACKGROUND This study aimed to evaluate the potential benefit, in terms of pain relief, of the new oral fast-release orodispersible galvanic form of tramadol in women undergoing hysterosalpingography (HSG) with either a metal cannula or a balloon catheter. METHODS In a randomized, double-blind, placebo-controlled, 2 x 2 factorial-design trial, conducted at a single academic centre, 128 women ...

New daily persistent headache (NDPH) is defined as a persistent and daily headache from onset. It is a unique headache that typically seen in people without a prior history of headaches. New daily persistent headache (NDPH) is an often medication-refractory headache disorder, currently classified as a primary headache disorder. Several medications including Onabotulinum toxin injections and sph...

Patients 397 patients who were 18–65 years of age, had a diagnosis of schizophrenia or schizoaffective disorder according to DSM-IV criteria, had required intensive psychiatric treatment within 24 months before study entry, had received a stable dose of antipsychotic medication for >30 days before study entry, had resided at the same address for >30 days before study entry, and were judged clin...

Objective To present a case series of children retrialed on stimulants after initial poor stimulant responses given the paucity of information on the usefulness of this strategy. Methods Health records from an ADHD medication service were obtained for six children who: (i) were medication naïve at service entry; (ii) had trials of at least one stimulant from each stimulant class; (iii) subseq...

OBJECTIVES To identify the prevalence of stimulant and antidepressant medication use by children and adolescents with symptoms meeting the criteria for attention-deficit/hyperactivity disorder (ADHD) and major depressive disorder (MDD) in Australia. To identify factors associated with stimulant and antidepressant use by children and adolescents in Australia. METHODS Data are from a nationally...

This report is an overview of the medication safety studies conducted by the VISN (Veterans Integrated Service Network) 8 Patient Safety Center of Inquiry (PSCI), Tampa, FL, over the past 5 years. The Center has been developing the research capacity to conduct national Veterans Health Administration (VHA) proactive medication safety surveillance studies as part of its research focus on patient ...

Converging theoretical, psychopharmacological, neurodevelopmental advances have led to increasing interest in preventive intervention in schizophrenia. In particular, evidence suggests that early treatment is associated with a better prognosis. Furthermore, based on the reported reduction in severe side effects, the new novel antipsychotics potentially provide the tools for early intervention. ...