the present paper is devoted to a new critical state based plasticity model able to predict drained and undrained behaviour of granular material. it incorporates a bounding surface plasticity model describing in multilaminate framework to capitalize on advantages of this mathematical framework. most of the models developed using stress/strain invariants are not capable of identifying the parame...

Recent work established DNA replication stress as a crucial driver of genomic instability and a key event at the onset of cancer. Post-translational modifications play an important role in the cellular response to replication stress by regulating the activity of key components to prevent replication-stress-induced DNA damage. Here, we establish a far greater role for transcriptional control in ...

introduction: brain-derived neurotrophic factor (bdnf) and its receptor, trkb, in the hippocampus are targets for adverse effects of stress paradigms in addition, bdnf and its receptor play key role in the pathology of brain diseases like depression. in the present study, we evaluated the possible role of hippocampal bdnf in depression during pregnancy, methods: to achieve the purpose, repeated...