Visual thinking plays an important role in scientiic reasoning. Based on the research in automating diverse reasoning tasks about dynamical systems, nonlinear controllers, kine-matic mechanisms, and uid motion, we have identiied a style of visual thinking, imagistic reasoning. Imagistic reasoning organizes computations around image-like, analogue representations so that perceptual and symbolic ...

Hodgkin and Reed-Sternberg (HRS) cells in Hodgkin lymphoma (HL) secrete factors that interact with inflammatory background cells and may serve as biomarkers for disease activity. To detect new proteins related to pathogenesis, we analyzed the secretome of HRS cells. Proteins in cell culture supernatant of 4 HL cell lines were identified using 1DGE followed by in-gel trypsin digestion and LC-MS/...

Sionnnary. A comiparative study was made of the efffects of auxin (a-naphthalene acetic acid), kinetin (6-furfurylaminopurine) and a mixture of auxin and kinetin applied in vivo on synthesis okf RNA and protein and the distribution of such synthesis am'ongst the subcellular fractions of sections of endocarp from Kentucky Wonder pole beans (Phascolus vulgaris, L.). Auxin caused considerable enha...

A summary is given of an analysis of the Hippar-cos trigonometrical parallaxes and proper motions of classical Cepheids. It is possible for the first time to derive zero-points for the period-luminosity and period-luminosity-colour relations from paral-laxes alone, avoiding the problems of less direct methods. The results imply an increase of 8 to 10 percent in the extragalactic distance scale ...

CINEGEN is a Virtual Reality based system for the rapid design, prototyping and simulation of robot manipula-tors. With CINEGEN, users provide a text description of a manipulator and a numerical algorithm automatically computes the inverse kinematics. This algorithm is capable of handling serial, parallel and hybrid manipulator structures. Using CINEGEN, the user can directly interact with a gr...

Cerebral malaria (CM) causes death in children and nonimmune adults. TNF-alpha has been thought to play a key role in the development of CM. In contrast, the role of the related cyto-kine lymphotoxin alpha (LTalpha) in CM has been overlooked. Here we show that LTalpha, not TNFalpha, is the principal mediator of murine CM. Mice deficient in TNFalpha (B6.TNFalpha-/-) were as susceptible to CM cau...

RUPTURE iS the usual cause of death in cases of dissecting aneurysm of the aorta in the acute stage. In Sheenan's series of 300 cases (1934) the pericardium was the commonest site of rupture, the pleural cavity being next in frequency. Sheenan described only two cases that survived intrapleural rupture of a dissecting aneurysm, one for 17 days, the other 19 days, and in a review of 505 cases of...

When suucient computing power is available, dynamic simulation can be used as a source of motion for real-time, interactive virtual environments. In this paper, we explore techniques for reducing the computational cost of simulating groups of creatures by using less accurate simulations for individuals when they are less important to the viewer or to the action in the virtual world. The less ac...

The b chemokine known as 6-C-kine, secondary lymphoid-tissue chemokine (SLC), TCA4, or Exodus-2 (herein referred to as 6CK/SLC) can trigger rapid integrin-dependent arrest of lymphocytes rolling under physiological shear and is highly expressed by high endothelial venules, specialized vessels involved in lymphocyte homing from the blood into lymph nodes and Peyer’s patches. We show that 6CK/SLC...