Oral Absorption and Disposition Kinetics of Lidocaine Hydrochloride in Dogs. R. N. BOYES, H. J. ADAMS AND B. R. DUCE 1 Maternal and Fetal Distribution of H3-Dihydromorphine in the Tolerant and Nontolerant Rat. S. Y. YEH AND L. A. WOODS 9 Retention of Inhaled Acetaldehyde in Man. JOHN L. EGLE, JR 14 Efflux of Chiorpromazine and Trifluoperazine from the Rat Brain. P. F. SPANO, N. H. NEFF, E. MACK...

Kinetics of P absorption were investigated in mycorrhizal (Glomus fasciculatus) and nonmycorrhizal tomato (Lycopersicon esculentum) roots to determine why increased ion absorption by mycorrhizae occurs. Initial rates of absorption of (32)P were measured at 1 to 100 micromolar KH(2)PO(4) (pH 4.6). Absorption rates of mycorrhizae were about twice those of control roots. Augustinsson-Hofstee analy...

BACKGROUND Pneumonia is the most common cause of death in patients with severe motor and intellectual disabilities (SMID), and intravenous ceftazidime (CAZ) is a widely used treatment for such infections. However, intravenous administration in patients with SMID may be difficult because of insufficient vascular development. OBJECTIVES The aim of our study was to determine the feasibility of s...

Poly(methyl methacrylate) (PMMA)/hydroxyapatite (HA) composite has potential application in denture base materials. The denture base materials should exhibit good mechanical properties and dimensional stability in moist environment. Silane coupling agent [3-methacryloxypropyltrimethoxy silane (γ-MPS)] was used to treat the HA fillers in order to enhance the interfacial interaction between the P...

In individuals with similar body stores of iron, the amount of iron absorbed from a single oral dose is not proportional to the amount of iron administered. Although a greater amount of iron is absorbed as the size of the oral dose increases, the percentage or fraction of the dose that is absorbed actually decreases (1-3). In addition, the amount of iron absorbed from a given dose is dependent ...

The kinetics of inhaled racemic formoterol and its effects on the size of the early cutaneous reaction to intradermal injection of an allergen, eosinopenia and hypokalemia were assessed by pharmacokinetic-pharmacodynamic modeling. After inhalation of either 120 microg of formoterol or placebo, blood samples were taken and skin tests were performed in seven healthy subjects. A two-compartment mo...