objective(s): this paper describes a selective and sensitive biosensor based on the dissolution and aggregation of aptamer wrapped single-walled carbon nanotubes. we report on the direct detection of aptamer–cocaine interactions, namely between a dna aptamer and cocaine molecules based on near-infrared absorption at λ807. materials and methods: first a dna aptamer recognizing cocaine was non-co...

While antibody-based fluorescence and radioactive detection technologies have dominated drug discovery and biological research worldwide, label-free technology is becoming widely accepted as a valuable research tool for mechanism-of-action (MOA) studies in lead optimization and receptor pharmacology. Here we introduce EnSpire® Multimode Plate Reader with Corning® Epic® label-free technology. Th...