PURPOSE The purpose of this study was to investigate the prevalence of a common canalicular entrance in the lacrimal sac and to investigate the anatomy of the canalicular/lacrimal sac junction with direct visualization using a novel cadaveric dissection technique. METHODS Preserved cadavers were dissected to allow direct visualization of the canalicular entrance(s) to the lumen of the lacrima...

Dear Editor, Two cases with epiphora and medial canthal mass showed a cyst within the lacrimal sac that compressed the lacrimal drainage system. We describe a new lacrimal sac anomaly of lacrimal intrasaccal cyst, which has not yet been reported. A 31-year-old woman was referred for epiphora in her left eye for 17 years. She also presented with a 10-year history of a palpable mass below the med...

BACKGROUND Study of human lacrimal cell biology is limited by poor access to tissue samples, heterogeneous cell composition of tissue and a lack of established lacrimal epithelial markers. In order to further our understanding of lacrimal cell biology, we sought to find a better marker for human lacrimal epithelial cells, compared to what has been reported in the literature. METHODS We utiliz...

BACKGROUND The study of human lacrimal gland biology and development is limited. Lacrimal gland tissue is damaged or poorly functional in a number of disease states including dry eye disease. Development of cell based therapies for lacrimal gland diseases requires a better understanding of the gene expression and signaling pathways in lacrimal gland. Differential gene expression analysis betwee...

In the present article, cases of lacrimal apparatus conditions emerging after a new Coronavirus infection COVID-19. The aim study is to determine causes epiphora in patients infection.
 26 (30 eyes) were examined, aged from 28 70 years, complaining tearing, which emerged for first time ever not earlier than 514 days onset laboratory-confirmed COVID-19, had mild or moderately severe course ...

The method of secretory granuleformation in the acinar cells of the rat exorbital lacrimal gland was studied by electron microscope morphological and cytochemical techniques. Immature secretory granules at the inner face of the Golgi apparatus were frequently attached to a narrow cisternal structure similar to GERL as described in neurons by Novikoff et al. (Novikoff, P. M., A. B. Novikoff, N. ...

OBJECTIVE To determine the usefulness of "routine" lacrimal sac biopsy to evaluate unsuspected neoplasm or systemic disease in patients with acquired nasolacrimal duct obstruction. DESIGN Noncomparative, interventional case series with histopathologic correlation. PARTICIPANTS Review of charts revealed histopathologic reports on 302 specimens from 258 patients who had undergone routine dacr...

BACKGROUND This chapter gives an overview about the structures and physiology of the ocular surface and its adnexa and focuses in a second part on the possible meaning of eye-associated lymphoid tissue (EALT) in a context with the development of dry eye. METHODS Sections deal with (1) anatomy of the ocular surface, lacrimal gland, eyelid and nasolacrimal ducts. (2) The meaning and importance ...