Unheated and heat-treated homogenates were separately prepared from candidate probiotic bacteria, including Lactobacillus rhamnosus GG, Bifidobacterium lactis, Lactobacillus acidophilus, Lactobacillus delbrueckii subsp. bulgaricus, and Streptococcus thermophilus. We compared the phytohemagglutinin-induced proliferation of mononuclear cells in the presence of homogenates and in the presence of a...

The gut microflora is an important constituent in the intestinal mucosal barrier and has been introduced as the concept of probiotic therapy that beneficially affects the host by improving its intestinal microbial balance. Therefore, the main objective of the study was to explore the protective potential of various lactobacilli strains for murine giardiasis. By experimentation, it was found tha...

OBJECTIVE The purpose of this randomized, double-blind, placebo-controlled study was to evaluate the influence of the orally administered probiotic strains Lactobacillus rhamnosus GR-1 and Lactobacillus reuteri RC-14 on the quality of the vaginal flora in postmenopausal women. STUDY DESIGN Postmenopausal women with Nugent scores between 4 and 6 in initial vaginal swab, were randomized into tw...

Both study designs were randomized, double-blind, placebo-controlled trials qualifying as a level of evidence Ia. In the study by Martinez, Franceschini, Patta, Quintana, Gomes, et al. (2009), half of the women received a single dose of tinidazole (2g) in addition to 2 placebo capsules while half received tinidazole (2g) supplemented with 2 capsules containing L. rhamnosus GR-1 and L. reuteri R...

Recent studies have shown that probiotics are beneficial in T-cell-mediated inflammatory diseases. The molecular mechanism by which probiotics work remains elusive, but accumulating evidence indicates that probiotics can modulate immune cell responses. Since T cells express receptors for bacterial products or components, we examined whether different strains of lactobacilli directly regulate th...

BACKGROUND Data regarding antimicrobial susceptibility of clinical Lactobacillus isolates are scarce, and appropriate interpretation criteria for susceptibility tests are not available. METHODS We examined 85 cases of Lactobacillus bacteremia, of which 47 cases have been included in our previous studies. Overall, 14 antimicrobial agents were evaluated by the E-test method, and these results w...

boulardii) Natural Standard Bottom Line Monograph, Copyright © 2012 (www.naturalstandard.com). Commercial distribution prohibited. This monograph is intended for informational purposes only, and should not be interpreted as specific medical advice. You should consult with a qualified healthcare provider before making decisions about therapies and/or health conditions. While some complementary a...

Lactic acid can be produced by fermentation of organic matters present in various wastes with the addition of various carbon and nitrogen sources using Lactobacillus species. Organic wastes form kitchen garbage and foodprocessing industries are especially rich in carbon and moisture content. The present study investigates the treatment of the organic wastes using microbiological process for eff...

Few studies have evaluated the potential benefits of the topical application of probiotic bacteria or material derived from them. We have investigated whether a probiotic bacterium, Lactobacillus rhamnosus GG, can inhibit Staphylococcus aureus infection of human primary keratinocytes in culture. When primary human keratinocytes were exposed to S. aureus, only 25% of the keratinocytes remained v...