نتایج جستجو برای: lagrangianlagrangian ll

تعداد نتایج: 9925  

Journal: :Publications of the Astronomical Society of Japan 2004

2011
Scott N. Dean Barney M. Bishop Monique L. van Hoek

Pseudomonas aeruginosa is a highly versatile opportunistic pathogen and its ability to produce biofilms is a direct impediment to the healing of wounds and recovery from infection. Interest in anti-microbial peptides (AMPs) has grown due to their potential therapeutic applications and their possible use against antibiotic resistant bacteria. LL-37 is the only cathelicidin expressed by humans. I...

Journal: :Experimental cell research 2011
Jamie S Mader Marcelo Marcet-Palacios Robert E W Hancock R Chris Bleackley

LL-37 is a human cationic host defense peptide (antimicrobial peptide) belonging to the cathelicidin family of peptides. In this study, LL-37 was shown to kill stimulated CD8(+) T cells (Cytotoxic T lymphocytes; CTLs) via apoptosis, while having no cytotoxic effect on non-stimulated CD8(+) or CD4(+) T cells or stimulated CD4(+) T cells. Of interest, the CD8(+) cells were much more sensitive to ...

Journal: :Logic Journal of the IGPL 1994
Vladimir Alexiev

This paper is an overview of existing applications of Linear Logic (LL) to issues of computation. After a substantial introduction to LL, it discusses the implications of LL to functional programming, logic programming, concurrent and object-oriented programming and some other applications of LL, like semantics of negation in LP, non-monotonic issues in AI planning, etc. Although the overview c...

2017
Eun-Jung Yang Sa-Ik Bang

Adipose stem cell-conditioned medium may promote human dermal fibroblast (HDF) proliferation and migration by activating paracrine peptides during the re-epithelization phase of wound healing. Human antimicrobial peptide LL-37 is upregulated in the skin epithelium as part of the normal response to injury. The effects of conditioned medium (CM) from LL-37 treated adipose stem cells (ASCs) on cut...

Journal: :Cancer research 1994
Y Sakaguchi M Makino T Kaneko L C Stephens F R Strebel L L Danhauser G N Jenkins J M Bull

This study examines the effects of a combined modality regimen of long duration-low temperature whole body hyperthermia (6 h at 40.0 degrees C; LL-WBH), recombinant human tumor necrosis factor-alpha (TNF) and carboplatin (CBDCA) on a transplantable fibrosarcoma as well as normal tissue. We compare LL-WBH with short duration-high temperature whole body hyperthermia (2 h at 41.5 degrees; SH-WBH)....

Journal: :Behavioural brain research 2009
Laura K Fonken M Sima Finy James C Walton Zachary M Weil Joanna L Workman Jessica Ross Randy J Nelson

Individuals are increasingly exposed to light at night. Exposure to constant light (LL) disrupts circadian rhythms of locomotor activity, body temperature, hormones, and the sleep-wake cycle in animals. Other behavioural responses to LL have been reported, but are inconsistent. The present experiment sought to determine whether LL produces changes in affective responses and whether behavioural ...

Journal: :Investigative ophthalmology & visual science 2010
Jia Yin Fu-Shin X Yu

Purpose. Patients with diabetes are at higher risk for delayed corneal reepithelialization and infection. Previous studies indicated that high glucose (HG) impairs epidermal growth factor receptor (EGFR) signaling and attenuates ex vivo corneal epithelial wound healing. The authors investigated the effects of antimicrobial peptide LL-37 on HG-attenuated corneal epithelial EGFR signaling and wou...

Journal: :Arteriosclerosis, thrombosis, and vascular biology 2006
Kristina Edfeldt Birgitta Agerberth Martin E Rottenberg Gudmundur H Gudmundsson Xiong-Biao Wang Kaushik Mandal Qingbo Xu Zhong-qun Yan

OBJECTIVE Antimicrobial peptides are effector molecules of the innate immune system. To understand the function of vascular innate immunity in atherosclerosis, we investigated the role of LL-37, a cathelicidin antimicrobial peptide, in the disease process. METHODS AND RESULTS Using real-time polymerase chain reaction, we found a 6-fold increase in human cationic antimicrobial protein 18/LL-37...

Journal: :The Journal of antimicrobial chemotherapy 2008
Robert Bucki Dorota B Namiot Zbigniew Namiot Paul B Savage Paul A Janmey

OBJECTIVES Cationic antimicrobial peptides (CAPs) are the effector molecules of innate immunity, similar in potency to classic antibiotics that function in the first-line of defence against infectious agents. The purpose of this study was to investigate the effects of negatively charged mucins on the antibacterial activity of the positively charged cathelicidin LL-37 peptide, its synthetic anal...

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