The physiopathology of postdural puncture headache (PDPH) is most likely multifaceted (1, 2). Understanding the mechanisms through which some subjects develop PDPH may help in the development of PDPH-prevention strategies. In addition, identifying risk factors in susceptible individuals may help develop forms of anesthesia other than spinal anesthesia for preventing dura mater/arachnoid perfora...

Migraine headaches are often precipitated by stress and seem to involve neurogenic inflammation (NI) of the dura mater associated with the sensation of throbbing pain. Trigeminal nerve stimulation had been reported to activate rat dura mast cells and increase vascular permeability, effects inhibited by neonatal pretreatment with capsaicin implicating sensory neuropeptides, such as substance P (...

The aim of the study was to explore keyhole approach and dura suture in the neuroendoscopic treatment for hydrocephalus.Twelve cases of hydrocephalus patients who were treated with neuroendoscope by this approach were analyzed retrospectively from April 2015 to April 2016 in our department. The basic steps of this procedure was using drill and milling cutter to form a small bone flap instead of...

BACKGROUND Idiopathic spinal cord herniation (ISCH) is a rare condition and its pathogenesis remains unclear. The purpose of this case report is to present an ISCH case with dorsal subarachnoid septum suggesting the pathogenesis of ISCH being adhesions from preexisting inflammation. METHODS Single case report. RESULTS A 60-year-old woman presented with Brown-Séquard syndrome below the level...

The dura layer which covers the brain is less conductive than the CSF (cerebrospinal fluid) and also more conductive than the skull bone. This could significantly influence the flow of volume currents from cortex to the scalp surface which will also change the magnitude and spatial profiles of scalp potentials. This was examined with a 3-D finite element method (FEM) model of an adult subject c...

This review considers the structure of the meninges, as seen at the electron microscopic level, with particular emphasis on the dura-arachnoid junction and whether a naturally occurring space is found at this interface. The classic view has been that a so-called subdural space is located between the arachnoid and dura and that subdural hematomas or hygromas are the result of blood or cerebrospi...

Neovascularization of the outer membrane plays a critical role in the development and enlargement of chronic subdural hematomas (CSHs) and vascular endothelial growth factor (VEGF) may promote their progression. However, the precise mechanisms remain to be determined. We focused on the signaling pathway upstream of VEGF, transforming growth factor β (TGF-β), and activin receptor-like kinase 1 (...