We describe our treatment of two boys with continuous spikes and waves during slow wave sleep (CSWS). One of the boys was suffering from non-convulsive status epilepticus and the other from conscious disturbance with automatism. Their ictal EEG readings showed continuous diffuse spike and wave complexes, which were considered to show electrical status. The boys were diagnosed as having CSWS, an...

PURPOSE The aim of the study was to retrospectively analyze the electroclinical features, etiology, treatment, and prognosis of 29 patients with Landau-Kleffner syndrome (LKS) with a long-term follow-up. METHODS Inclusion criteria were a diagnosis of LKS with: (1) acquired aphasia or verbal auditory aphasia; (2) with or without focal seizures, secondarily generalized tonic-clonic seizures, ab...

PURPOSE EEG studies based on adult populations report interictal epileptiform discharges (EDS) favour the left hemisphere. It is not clear when favouring becomes apparent as similar paediatric studies have not been performed. METHODS The authors reviewed 1,579 paediatric EEG interpretations for evidence of hemispheric favouring of focal epileptiform discharges. Analysis focused on first-time ...

Flunarizine is a non selective calcium channel antagonist. It is highly lipophilic compound which distributes preferentially in adipose tissue and passes the blood brain barrier readily. Numerous preclinical and controlled clinical studies, including double blind clinical studies in which the drug was compared with placebo or standard drugs in particular disease showing efficacy in migraine, ve...

Medical/neurological evaluation is mandatory. • Head circumference (e.g., microcephaly in Rett’s), dysmorphism in syndromic ASD (e.g., phakomatosis, mitochondrial encephalopathy) • Electroencephalography ‐for epileptiform discharges or seizures (typically bimodal, 8‐21.5% have epilepsy and more in females)[3] also indicated in regression and Landau–Kleffner syndrome • ENT evaluation should be d...

Landau-Kleffner Syndrome (LKS) is a rare, childhood neurological disorder characterized by a sudden or gradual development of acquired aphasia. This case study offers a unique opportunity to assess the changes in the auditory processing ability of a 12 year old male with LKS after two distinct auditory training programs, Fast ForWord® and Dichotic Interaural Intensity Difference (DIID) training...

This article is concerned with the time evolution of the oblique laminar-turbulent bands of transitional plane Couette flow under the influence of turbulent noise. Our study is focused on the amplitude of modulation of turbulence (the bands). In order to guide the numerical study of the flow, we first perform an analytical and numerical analysis of a Stochastic Ginzburg-Landau (GL) equation for...

Epileptic encephalopathies are an epileptic condition characterized by epileptiform abnormalities associated with progressive cerebral dysfunction. In the classification of the International League Against Epilepsy eight age-related epileptic encephalopathy syndromes are recognized. These syndromes include early myoclonic encephalopathy and Ohtahara syndrome in the neonatal period, West syndrom...