OBJECTIVES We investigated the incidence of Epstein-Barr virus (EBV) infection in surgical specimens of squamous cell carcinoma of the larynx and vocal cord nodules. PATIENTS AND METHODS Formalin-fixed, paraffin-embedded tissue samples randomly selected from 22 patients with squamous cell carcinoma of the larynx (20 males, 2 females; mean age 52 years) and from 17 patients with vocal cord nod...

INTRODUCTION Sentinel node mapping has been used for laryngeal carcinoma in several studies, with excellent results thus far. In the current study, we report our preliminary results on sentinel node mapping in laryngeal carcinoma using intra-operative peri-tumoral injection of a radiotracer. MATERIALS AND METHODS Patients with biopsy-proven squamous cell carcinoma of the larynx were included ...

abstract   background: nasopharyngeal carcinoma (npc) is a nonlymphomatous squamous cell carcinoma (scc) that occurs in the epithelial lining of the nasopharynx. viral, geographic, and ethnic factors are responsible for its multifactorial futures. previous studies have showed the role of epstein-barr virus (ebv) in the pathogenesis of npc but no study has been conducted on the iranian populatio...

Introduction: Cigarette smoking and alcohol consumption have a well-known effect on the development of upper aerodigestive tract carcinomas, but such a role for opium is questionable. This study was designed to assess the correlation between opium inhalation and cancer of the larynx and upper esophagus. Materials and Methods: Fifty eight patients with laryngeal cancer, ninety eight patients wit...

Although the association and clinical significance of human papillomavirus (HPV) infections with a subset of head and neck cancers, particularly for oropharyngeal carcinoma, has recently been well documented, the involvement of HPV in laryngeal cancer has been inadequately evaluated. Herein we review the currently known associations of HPV infections in diseases of the larynx and their potentia...

BACKGROUND Tumour angiogenesis is the result of an inbalance between anti- and pro-angiogenic factors. CD105 (endoglin) is a component of the receptor complex of transforming growth factor (TGF-beta1). Vascular endothelial growth factor receptor 2 (VEGFR2 or Flk-1/KDR) belongs to the high-affinity VEGF receptors. The aim of the study was to investigate the expression, cellular localization and ...

Laryngeal carcinoma and laryngeal papilloma are the most commonly encountered tumorous lesions in the larynx. Herein, we report a case of the mass arising from the left vocal cord in a 49-year-old Japanese man. Endoscopic examination suggested that the mass is a tumor such as carcinoma and papilloma. Pathological examination showed that the specimen demonstrated actinomycosis in the left vocal ...

UNLABELLED Laryngeal squamous cell carcinoma is very often diagnosed at advanced stages. The time interval between the specialist consultation and the start of treatment may contribute to better outcomes. AIM the interval assessment between the first specialist evaluation and the treatment of patients with laryngeal squamous cell carcinoma. STUDY DESIGN longitudinal historical cohort. MAT...

Adenoid cystic carcinomas are malignant tumours and occur in the major and the minor salivary glands. Laryngeal adenoid cystic carcinomas are rare and account for less than 1% of all malignant tumours in the larynx. Adenoid cystic carcinoma is characterised by slow progression, multiple recurrences and late distant metastasis. The aetiology of adenoid cystic carcinoma remains unknown. They usua...

BACKGROUND The purpose of this study was to evaluate the functional and oncological outcomes of patients treated for T3 laryngeal squamous cell carcinoma. Specifically comparing transoral laser microsurgery and radiotherapy/chemoradiotherapy treatment modalities. METHOD A retrospective review of patients treated for T3 laryngeal SCC between 2002 and 2010 was undertaken. RESULTS Forty-nine p...