PURPOSE To describe the risk of early- and late-onset preeclampsia across pregnancies exposed to antidepressants and to evaluate the impact of timing and length of gestational exposure to antidepressants, particularly selective serotonin reuptake inhibitors (SSRIs), on preeclampsia. METHODS The Norwegian Mother and Child Cohort, a prospective population-based study, and the Medical Birth Regi...

Oxytocin (OT), a nanopeptide hormone, plays a role in the emergence of maternal behavior, yet few studies examined OT in humans across pregnancy and the postpartum. We followed healthy women at three points: first trimester of pregnancy, third trimester, and first postpartum month. Plasma OT levels showed high individual stability. A third of the sample showed consistent OT levels, whereas othe...

Placentitis is estimated to affect 3 to 5% of pregnancies in Thoroughbred mares Late-term pregnancy wastage generates several million dollars of losses to the lost expense of producing a pregnancy (e.g. stud fees, semen transport, feed, vaccinations, veterinary services, etc.) Late term pregnancy loss may cause emotional stress to the owner with high expectations for the foal from a particular ...

OBJECTIVES To investigate whether the timing of probiotic milk intake before, during early or late pregnancy influences associations with preeclampsia and preterm delivery. DESIGN Population based prospective cohort study. SETTING Norway, between 1999 and 2008. PARTICIPANTS 70 149 singleton pregnancies resulting in live-born babies from the Norwegian Mother and Child Cohort Study (no chro...

During pregnancy, many women gain excessive weight, which is related to adverse maternal and neonatal outcomes. In this study, we evaluated whether rate of gestational weight gain (RGWG) in early, mid, and late pregnancy is strongly associated with adverse pregnancy outcomes. A retrospective chart review of 2,789 pregnant Korean women was performed. Weights were recorded at the first clinic vis...

Sir, Patients undergoing chronic dialysis often believe they are unable to conceive, because of irregular menstruations and decreased libido; consequently, they do not regularly use contraceptive methods. Pregnancy is detected late, particularly in patients on peritoneal dialysis [1]. Early detection of pregnancy in dialysis patients is very important, in order to choose adequate methods for fo...

BACKGROUND Although the hypertrophic responses of the heart to pregnancy and exercise are both considered to be physiological processes, they occur in quite different hormonal and temporal settings. In this study, we have compared the global transcriptional profiles of left ventricular tissues at various time points during the progression of hypertrophy in exercise and pregnancy. METHODOLOGY/...

BACKGROUND Current markers of iron deficiency tend to be less reliable in pregnancy. OBJECTIVE Our aim was to study the usefulness of soluble serum transferrin receptor (sTfR) as a marker for iron deficiency during early and late gestation and to define iron status in 254 pregnant Swedish women. DESIGN We performed a cross-sectional and longitudinal evaluation of sTfR in comparison with con...

In Victoria, decisions regarding late termination of pregnancy no longer involve just pregnant women and their clinicians. At two major women's hospitals, committees now govern the decision-making process for approval of a late termination of pregnancy. The legal and ethical implications of clinical decision-making by committee need to be widely debated.

Prior DNA methylation (DNA-m) analyses have identified cytosine-phosphate-guanine (CpG) sites, which show either a significant change or consistency during lifetime. However, the proportion of CpGs that are neither significantly different nor consistent over time (indifferent CpGs) is unknown. We investigated the methylation dynamics, both longitudinal changes and consistency, in women from pre...