Although conceived at the end of the 19th century as a synthetic analgesic agent with improved gastric tolerability vs. naturally occurring salicylates, acetylsalicylic acid (marketed as aspirin in 1899) turned out to be an ideal antiplatelet agent about 90 years later, following the understanding of its mechanism of action, the development of a mechanism-based biomarker for dose-finding studie...

housing for LGBT elders. Generations, 29(4), 65–70. de Vries, B. (2007). LGBT couples in later life: A study in diversity. Generations, 31(3), 18–23. de Vries, B., & Blando, J. A. (2004). The study of gay and lesbian lives: Lessons for social gerontology. In G. Herdt & B. de Vries (Eds.), Gay and lesbian aging: research and future directions (pp. 3–28). New York: Springer. de Vries, B., & Hocte...

Epilepsy is most likely to develop in later life. The burden of this disorder on health-care resources will rise further as the world's population continues to age. Making a secure diagnosis can be challenging because the clinical manifestations of seizures and the differential diagnoses and causes of epilepsy can be different in older individuals compared with younger individuals. Obtaining a ...

The theory of abstract Case in the framework of Government and Binding played an important role in capturing cross-linguistic generalizations regarding order and constituency and accommodating exceptions to word order universals. Case was shown to be relevant even in languages without morphological case markings. Indeed, Li (1985, 1990) demonstrated that Case facilitated the understading of a w...

ike a picky tourist looking for a hotel room, the malariacausing protozoan Plasmodium passes through several cells before settling on one to infect. Margarida Carrolo, Maria Mota (Instituto Gulbenkian de Ciência, Oeiras, Portugal), and colleagues now report that the initial invasions cause the damaged cells to make a factor that primes other cells for infection. The factor turned up in culture ...

or the better part of my career I’ve traveled the world speaking to companies about security; their challenges, strengths, and weaknesses, the regulatory landscape, and technical infrastructures. Ultimately, while the languages may differ as much as the landscape, the security troubles and goals are extraordinarily similar, seemingly unaffected by the diversity in industry and law. But, given t...

Though common sense suggests that positive thinking shelters people from depression, the four studies reported here showed that this intuition needs to be qualified: Positive thinking in the form of fantasies about the future did indeed relate to decreased symptoms of depression when measured concurrently; however, positive fantasies predicted more depressive symptoms when measured longitudinal...

Two sets of measurements evaluated performance on typographically inverted text that students had learned to read 13 to IS months earlier. In one set, speed of reading was compared for pages read for the first and second times. Reread pages were read more quickly, thereby revealing an exceptional degree of memory at the pattern-analyzing level. In the second set of measurements, the readers cla...

In this paper, we report on the status of the RoboCupJunior league, four years after it was founded. Since its inception in 2000, we have been surveying and/or interviewing students and mentors who participate in the international event. Here we present a high-level overview of this data. We discuss demographics of participants, characteristics of preparation and educational value. We highlight...