Anthelmintic efficacy of levamisole, albendazole, ivermectin and morantel tartrate was evaluated in 75 sheep naturally parasitized with Haemonchus, Trichostrongylus, Oesophagostomum and Ostertagia spp. Results revealed that levamisole, albendazole, ivermectin and morantel tartrate were lOO, 98.82, 97.02 and 76.50 per cent effective, respectively in reducing the eggs per gram of faeces. The anim...

The structure of the title compound, C(11)H(12)BrN(2)S(+)·C(2)HO(4) (-) (common name 6-bromo-levamisole hydrogen oxalate), is stabilized mainly by hydrogen bonds. Hydrogen oxalate anions form parallel coplanar chains via O-H⋯O hydrogen bonds, while there are N-H⋯O hydrogen-bonding inter-actions between the 6-bromo-levamisole cations and oxalate anions. Both five-membered rings from the 6-bromo-...

A 5 1/2-year-old girl, with a life-long history of recurrent staphylococcal infections and eczematous dermatitis had a defect in polymorphonuclear leucocyte chemotaxis and phagocytosis in autologous serum, a high serum IgE level, and a disturbed T cell function. Levamisole improved all the immunological abnormalities and there was a dramatic clinical improvement. Discontinuation of therapy with...

DESCRIPTION A 43-year-old-man presented with 1-month history of progressive erythematous painful lesions over multiple sites involving bilateral lower extremities, trunk and pinnae. He was a chronic cocaine user; last use was 3 days prior to presentation. On examination he had bilateral large retiform, geometric, dusky, erythematous, tender plaques with central necrosis and ecchymosis over afor...

INTRODUCTION. Childhood idiopathic nephrotic syndrome is characterized by frequent relapsing courses or steroid dependency. Levamisole is a popular drug for treatment of these patients. The purpose of this study was to evaluate levamisole in children with steroid-dependent nephrotic syndrome. MATERIALS AND METHODS. We retrospectively studied 304 children with a diagnosis of steroid-dependent ne...

There are many reports that show the teratogenic effects of phenobarbital can be decreased by stimulation of maternal immune system. Therefore, in this study, the prophylactic effects of levamisole and vitamin E on teratogenic effects of phenobarbital were compared. This study was performed on 20 pregnant rats that were divided into four groups. Control group received normal saline and test gro...

PURPOSE To study the stability of levamisole oral solutions (25 mg/mL) prepared from powder and tablets stored at 4 +/- 3 degrees C and 23 +/- 2 degrees C in amber glass prescription bottles. METHODS Levamisole 25 mg/mL solutions were prepared from commercially available 50-mg tablets or from pure powder in sterile water. Levamisole concentrations were determined in duplicate by a stability-i...

There are many reports that show the teratogenic effects of phenobarbital can be decreased by stimulation of maternal immune system. Therefore, in this study, the prophylactic effects of levamisole and vitamin E on teratogenic effects of phenobarbital were compared. This study was performed on 20 pregnant rats that were divided into four groups. Control group received normal saline and test gro...