نتایج جستجو برای: lgals3
تعداد نتایج: 249 فیلتر نتایج به سال:
The most common sub-variant of papillary thyroid carcinoma (PTC) is the so-called follicular variant (FVPTC), which is a particularly problematic lesion and can be challenging from a diagnostic viewpoint even in resected lesions. Although fine needle aspiration cytology is very useful in the diagnosis of PTC, its accuracy and utility would be greatly facilitated by the development of specific m...
Polycomb repressive complex 2 (PRC2) catalyzes the monomethylation, dimethylation, and trimethylation of histone H3 Lys27 (H3K27) and acts as a central epigenetic regulator that marks the repressive chromatin domain. Embryonic ectoderm development (EED), an essential component of PRC2, interacts with trimethylated H3K27 (H3K27me3) through the aromatic cage structure composed of its three aromat...
هدف: هدف از این تحقیق شناسایی ژنهای ناحیه 2 دارای عدم تعادل آللیک با استفاده از روشهای بیوانفورماتیک و سپس انتخاب و مطالعه برخی از آنها با استفاده از روش هیبریداسیون درجا بود. مواد و روشها: تومورهای تائید شده توسط متخصص پاتولوژی برای کشت سلولی مورد استفاده قرار گرفت. کروموزومهای متافازی با روشهای متداول تهیه گردید. سپس پراب ژنهای مربوطه نشاندار شده جهت انجام هیبریداسیون بر روی اسلایدها...
The diagnosis of early mycosis fungoides (MF), the most common primary cutaneous T-cell lymphoma, is often delayed due to clinical and histopathological similarities with benign inflammatory dermatoses. Moreover, its clear delineation from spectrum so-called “parapsoriasis” still controversial. For further insight on a molecular level, we performed single-cell RNA sequencing profile skin biopsi...
هدف: هدف از این تحقیق شناسایی ژنهای ناحیه 2 دارای عدم تعادل آللیک با استفاده از روشهای بیوانفورماتیک و سپس انتخاب و مطالعه برخی از آنها با استفاده از روش هیبریداسیون درجا بود. مواد و روشها: تومورهای تائید شده توسط متخصص پاتولوژی برای کشت سلولی مورد استفاده قرار گرفت. کروموزومهای متافازی با روشهای متداول تهیه گردید. سپس پراب ژنهای مربوطه نشاندار شده جهت انجام هیبریداسیون بر روی اسلایدها ...
Abstract Background and Aims Chronic kidney disease (CKD) is a major health problem worldwide. The last stage of CKD end-stage renal (ESRD), which characterized by progressive decrease in glomerular filtration rate (GFR). End-stage failure often complicated anemia, uremic cardiomyopathy, osteodystrophy, can be fatal. Therefore, it necessary to identify the risk factors that lead ESRD or death. ...
The pathologic presentations of cutaneous T-cell lymphoma (CTCL) are heterogenous, ranging from indolent mycosis fungoides (MF) to transformed (LCT). Folliculotropic (FMF) is a rare variant MF, characterized by the involvement hair follicles, with variable presentation, including alopecia, follicular papules, and multiple abscesses. therapeutic response in FMF highly molecular etiology disease ...
The EGFR-mediated signaling pathways are important in a variety of cellular processes, including cell migration and wound re-epithelialization. Intracellular trafficking of EGFR is critical for maintaining EGFR surface expression. Galectin-3, a member of an animal lectin family, has been implicated in a number of physiological and pathological processes. Through studies of galectin-3-deficient ...
Galectin-3 is a ß-galactoside-specific lectin implicated in diverse pro cesses involved in cellular interactions. Recently, the Mac-2-binding pro tein, a heavily /V-glycosylated secreted protein with a subunit MTof 97,000, was identified as its ligand. The present study characterizes the interaction between galectin-3 and Mac-2-binding protein in whole cells and measures their relative express...
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