Rosai-Dorfman disease (RDD) is a rare condition that causes massive lymphadenopathy, most commonly in the cervical area. Cowden syndrome (CS) hamartomas skin and mucosa predisposes individuals to various malignancies. Lhermitte-Duclos (LDD), or dysplastic cerebellar gangliocytoma, often associated with CS. A 41-year-old female all three conditions presented abnormal uterine bleeding endometrial...

thesis, but had normal CSF albumin and normal plasma proteins. Similar changes often occur in multiple sclerosis and other chronic and subacute inflammatory diseases of the nervous system but are usually of lesser degree than those observed in our patient.16 Elevations of CSF gamma globulin to levels higher than 30% of the total protein are very unusual in neurological disorders other than suba...

A 57-year-old woman with a history of hypothyroidism, hysterectomy and depression presented to the emergency department (ED) with 3 months of progressive vertigo, ataxia and posterior headache. The patient denied fever, weight loss, vision difficulty or trauma. The patient was directed to the ED because of an abnormal outpatient MRI done earlier that day obtained by her family physician. The pa...

Farhad Assarzadegan, Atoosa Gharib, Shirin Behbahani, Meysam Ebrahimi-Abyaneh 1 Department of Neurology, Imam Hossein Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran 2 Department of Pathology, Imam Hossein Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran 3 Department of Neurosurgery, Imam Hossein Hospital, Shahid Beheshti University of Medical Scienc...

A 42-year-old female presented with complaints of mild occipital headaches of severe months duration. There were no cutaneous lesions or significant family history suggesting any genetic disease. On examination, she did not have any papilloedema, dymetria, dysdiadokokinasia or ataxia. Her cranial nerve examination was normal. On non-enhanced computed tomogram (CT) showed a mildly hyperdense wel...

OBJECTIVE: A rare case of LDD confirmed by biopsy is being reported. Review of the published cases shows that the disease usually manifests by the signs of increased intracranial pressure with inconstant cerebellar symptoms. MRI is the imaging modality of choice by now. As such, clinical problems after gross total or complete removal have not been reported so far, but herein we stress the impor...