background and aims. lichen planus is a relatively common chronic mucocutaneaous disease with an unknown cause, and is considered a manifestation of cell-mediated immune response. hepatitis c virus (hcv) and its subgroups have been associated with lichen planus in different geographic locations. the present study was undertaken to evaluate the prevalence of hcv antibody in patients with lichen ...

background and aims. oral lichen planus is a relatively common chronic oral mucosal disease of unknown etiology. regarding numerous studies on the immunologic factors involved in the etiology of lichen planus, the present study evaluated the serum interleukin-17 (il-17) level in patients with erosive and non-erosive oral lichen planus. materials and methods. this descriptive analytical study in...

DOI: 10.4103/2229-5178.209617 and Analysis of 38 Cases. Dermatol Surg 2015;41:1411‐8. 3. Tong LX, Weinstock M, Drews R, Sheikine Y, Kim CC. Widely metastatic squamous cell carcinoma originating from malignant transformation of hypertrophic lichen planus in a 24‐year‐old woman: Case report and review of the literature. Pediatr Dermatol 2015;32:e98‐101. 4. Wörheide J, Bonsmann G, Kolde G, Hamm H....

STATEMENT OF PROBLEM Lichen planus is a chronic inflammatory immunologic-based disease involving skin and mucosa. This disease is generally divided into two categories: erosive and non-erosive. Many etiologic factors are deliberated regarding the disease; however, the disorders of immune system and the role of cytotoxic T-lymphocytes and monocytes are more highlighted. Zinc is an imperative ele...

lichen planus (lp) is a chronic mucocutaneous disease widely recognized in adults, but uncommon in children. the purpose of this paper is to report two cases of lp in children. the diagnosis was made based on clinical and histopathological findings. the treatment consisted of antifungal and multivitamin therapy. regression of lesions was observed. the patients are still under follow up. althoug...

Lichen planus (LP) is a common disorder in which auto-cytotoxic T lymphocytes trigger apoptosis of epithelial cells leading to chronic inflammation. Oral Lichen Planus (OLP) can be a source of severe morbidity and has a small potential to be malignant. The diagnosis of OLP can be made from the clinical features if they are sufficiently characterized, but biopsy is recommended to confirm the dia...

UNLABELLED Oral lichen planus is one of the most common dermatological diseases presenting in the oral cavity; the prevalence in the general population is 1% to 2%. Although relatively frequent, oral lichen planus is the target of much controversy, especially in relation to its potential for malignancy. AIM This study aimed to make clinical and histopathological considerations regarding oral ...

HLP: hypertrophic lichen planus LP: lichen planus PEH: pseudoepitheliomatous hyperplasia SCC: squamous cell carcinoma INTRODUCTION Hypertrophic lichen planus (HLP) and squamous cell carcinoma (SCC) share many clinical and histopathologic characteristics, making them difficult to distinguish. HLP may undergo malignant transformation, leading to the development of SCC within HLP. We present a cas...

Background: Oral Lichen Planus (OLP) is a chronic autoimmune disease that could be considered as a potential premalignant status. Objective: To evaluate the miRNA-146a and miRNA-155 expression levels in patients with oral Lichen planus lesions compared to healthy subjects with normal oral mucosa. Methods: Forty patients with oral lichen planus and 18 healthy age and gender-matched controls were...

The aim of this case report is to present a histologically diagnosed oral lichen planus excised by the CO2 laser. Oral lichen planus is a chronic inflammatory mucocutaneous disease of unknown etiology. Different treatments have been used to manage this condition. A 46 year-old female was referred to the Laser Clinic of the Dental School of the Federal University of Bahia to excise a lesion char...