Background: Brucella sps are Gram negative, facultative intracellular bacteria causing brucellosis in humans and animals. Since it is a multi-organ disease and symptoms are nonspecific the diagnosis by clinical finding is difficult and can be missed .Many serological tests have been used form the diagnosis of human brucellosis. This study compared the diagnostic value of in-house ELISA and IFA ...

background: toxoplasmosis is a parasitic disease caused by protozoan, toxoplasma gondii. infections of human are common and are usually asymptomatic. the infection may be serious if is transmitted to the fetus during pregnancy. prophylactic measures, early detection of the infection and treatment can avoid congenital toxoplasmosis and many long term effects. objective: seroepidemiological study...

introduction: chlamydia is an important cause of sexually transmitted diseases leading to tubal factor infertility. background: this study aims to define the role of chlamydial antibody detection in predicting presence, nature and type of tubal pathology in laparoscopy. materials and methods: a prospective study was conducted on 200 consecutive patients undergoing laparoscopy as a part of infer...

background: the relationships between adiponectin and clinical outcomes in hemodialysis (hd) patients remain highly controversial. meanwhile, the association between adiponectin and the peripheral artery disease (pad) has not been well studied in hd patients without diabetic mellitus. materials and methods: the ankle-brachial index was measured in hd patients. adiponectin levels in 105 hd patie...

Background: Inflammation is involved in development, progression, and complications of atherosclerotic disease. Clinical studies have indicated that the level of monocyte chemoattractant protein 1 (MCP-1), IL-18, and adhesion molecules correlates with the severity of atherosclerosis and can predict future cardiovascular events. Experimental studies have shown pentoxifylline (PTX) reduces these ...

Background: Toxoplasmosis is a parasitic disease caused by protozoan, Toxoplasma gondii. Infections of human are common and are usually asymptomatic. The infection may be serious if is transmitted to the fetus during pregnancy. Prophylactic measures, early detection of the infection and treatment can avoid congenital toxoplasmosis and many long term effects. Objective: Seroepidemiological study...

Background: Streptokinase, which is injected intravenously with a standard dose of 1.5 MIU, is the most widely used thrombolytic agent around the world. What is so important about this bioproduct is the level of antistreptokinase (anti-sk) antibody in the population, which is directly correlated to the incidence of streptococcal infections in that population. Objective: Since Iran is an endemic...

Introduction: To recognize the predisposing factors in tuberculosis as an endemic infection in Northeast province of Iran, this study was aimed to evaluate whether HumanT-lymphocyte type 1 (HTLV-I) as an immunosuppressive factor increases the risk of tuberculosis. Materials and Methods: A Case-control study was conducted in 278 tuberculosis patients from 2007 to 2010, in Mashhad, Iran. Tubercul...

An enzyme-linked immunosorbent assay for neopterin using penicillinase as marker enzyme is reported here by polyclonal antibodies against neopterin conjugated to bovine serum albumin which were raised in rabbits. Immunoglobulin fractions were purified and coated on wells of microtiter plates. A chain heterology was introduced in neopterin derivative and conjugated to penicillinase. The assa...

Postheparin plasma is a convenient source for the measurement of lipoprotein lipase (LPL) in humans. Previous studies have focused on the measurement of LPL catalytic activity, and have been unable to conveniently measure the LPL protein or identify possibly different plasma forms of the enzyme. Preand postheparin plasma was treated with a highly specific antibody raised against bovine milk LPL...