Title of Thesis : INFLUENCE OF LIPOPROTEIN LIPIDS AND APOLIPOPROTEIN E GENE POLYMORPHISMS ON COAGULATION FACTOR VIII CHANGES WITH SIX MONTHS OF AEROBIC EXERCISE TRAINING. Rakesh Gopinathannair, Master of Arts, 2004. Thesis directed by: Professor James M. Hagberg, Ph.D., Dept. of Kinesiology Elevated plasma factor VIII antigen (FVIII:Ag) level is an independent risk factor for coronary artery di...

OBJECTIVE The objective of this study was to evaluate the effect of polymorphism S447X on plasma lipids of patients with premature coronary artery disease (CAD). METHODS Plasma lipids and genotypes were determined in 2 groups: 313 patients with premature CAD (<55 years of age) and 150 controls without CAD. RESULTS Frequency of the S447X polymorphism was 18% in patients with CAD and 23% in t...

Background Patients with rheumatoid arthritis (RA) have an increased risk for developing cardiovascular diseases (CVD). This is partly due to the systemic inflammation characteristic disease, but also prevalence of ‘traditional’ factors such as dyslipidemia. The in RA often leads catabolism lipids, resulting a subsequent decrease HDL and LDL, while treatment anti-inflammatory medication reverse...

introduction: in order to study the effects of turpentine oil on the concentration of lipids and lipoproteins of rabbit ( as an animal model for human studies )35 healthy female rabbits were chosen and then randomly allocated into 13 groups. different percents of turpentine oil and other oil compounds like vegetable oil, cholesterol and animal oil were given to each group ( 5 rabbits ) separate...

G.D. Lopaschuk and N.S. Dhalla (eds.), Cardiac Energy Metabolism in Health and Disease, Advances in Biochemistry in Health and Disease 11, DOI 10.1007/978-1-4939-1227-8_2, © Springer Science+Business Media New York 2014 Abstract Lipids are the major substrate for cardiac ATP production and they are derived from adipose tissue or lipoprotein triglycerides. Lipoproteins are synthesized in the liv...

OBJECTIVE The liver is one of the critical organs for lipoprotein metabolism and a major source for phospholipid transfer protein (PLTP) expression. The effect of liver-specific PLTP deficiency on plasma lipoprotein production and metabolism in mice was investigated. APPROACH AND RESULTS We created a liver-specific PLTP-deficient mouse model. We measured plasma high-density lipoprotein (HDL) ...

Blood lipids are useful biochemical indicators for assessing the risk of a number of chronic diseases, particularly those associated with obesity. In a multicenter case-control study that included 256 cases and 185 controls less than 75 years old, we studied the risk of endometrial cancer in relation to serum cholesterol, low density lipoprotein cholesterol, high density lipoprotein cholesterol...

BACKGROUND Metabolic symptoms induced by antipsychotic medication have been widely documented but there have been few studies comparing the effect of commonly used atypical antipsychotics on blood glucose and lipids among individuals with first-onset schizophrenia. METHODS A total of 150 patients with first-onset schizophrenia were randomized into three groups and each group was treated with ...

BACKGROUND AND PURPOSE The role of lipoprotein abnormalities in the development of ischemic cerebrovascular disease has not been sufficiently clarified. The aim of this study was to identify the lipoprotein profile in ischemic cerebrovascular disease and the possible role of apolipoprotein E polymorphism. METHODS The relation between the concentrations of lipoprotein(a), intermediate density ...

background: in this study, we evaluated the quality of care and control of cardiovascular risk factors in newly diagnosed diabetic patients, identified during diabetes screening program, 1 year after diagnosis. methods: in this prospective study, 83 newly diagnosed diabetic patients identified at screening in isfahan, were studied. height, weight, blood pressure, plasma glucose, lipids, and hem...