jung-taek kwon laboratory of toxicology, college of veterinary medicine, seoul 151-742, korea. hu-lin jiang 1- laboratory of toxicology, college of veterinary medicine, seoul 151-742, korea. 2- school of pharmacy, china pharmaceutical university, nanjing 210009, china. arash minai-tehrani laboratory of toxicology, college of veterinary medicine, seoul 151-742, korea. chang gyu woo nanotechnology and thermal processing laboratory, school of mechanical and aerospace engineering, seoul 151-742, korea. mansoo choi nanotechnology and thermal processing laboratory, school of mechanical and aerospace engineering, seoul 151-742, korea. chong-su cho research institute for agriculture and life sciences, seoul national university, seoul 151-742, korea.