Dengue virus, the causative agent of dengue fever (DF) and more severe forms of the disease – dengue haemorrhagic fever (DHF) and dengue shock syndrome (DSS) – can infect a number of different types of cells. While monocytes and macrophages are considered to be primary target cells driving the pathology of the disease, numerous studies have implicated the liver as a site of dengue virus replica...

The paper proposes a technology for analyzing ultrasound images based on textural characteristics the development of medical decision-making system determining presence pathological changes in diffuse liver diseases. list algorithmic solutions known and proposed by authors formation selection informative features was applied, version Random Forest classification algorithm developed, which achie...

Liver biopsy plays a central role in treatment algorithms in patients with hepatitis B and remains the gold standard for evaluating hepatic pathology. The pathology of hepatitis B is diverse and reflects the natural history of infection. An acute hepatitic pattern with lobular disarray is seen in acute infection, during acute flares of disease, and with acute hepatitis D superinfection. In chro...

Mice infected with an adenovirus mutant in which the E3 region is deleted, including TNF-resistance genes, develop fatal liver pathology within 3-4 days after infection. At least 10-fold more wild-type virus was needed to cause comparable pathology. These results indicate that the E3 region is critically involved in modulating the pathogenesis of adenovirus infection and that TNF may play a rol...

Alcohol use disorders affect millions of individuals worldwide. The impact these facts lies in the elevated social and economic costs. Liver metabolizes 75-98 % ethanol that enters organism. If level alcohol liver cells exceeds its degradation rate, alcoholic disease develops.
 aim study was to determine peculiarities hepatotoxicity after simulation hepatosis non-alcoholic steatohepatitis ...

Pathology Artificial Intelligence Platform (PAIP) is a free research platform in support of pathological artificial intelligence (AI). The main goal the to construct high-quality pathology learning data set that will allow greater accessibility. PAIP Liver Cancer Segmentation Challenge, organized conjunction with Medical Image Computing and Computer Assisted Intervention Society (MICCAI 2019), ...

Spontaneous bacterial empyema is defined as infection of the liver hydrothorax in cirrhotic patients. It a rare cause decompensated cirrhosis, with few bibliographic reports region, and its presence marks turning point inflection evolution disease poor prognosis short term. Two clinical cases patients this complication are presented, which were referred to National Liver Transplant Program Urug...

conclusion according to the results of our series, percutaneous liver biopsy using the tru-cut biopsy gun guided by ultrasonography can be performed safely. we resolve that routine ultrasound of the puncture site is a quick, effective and safe procedure. the complication rate is very low. the us-assisted percutaneous liver biopsy should be used for all cases. results a total of 1018 patients we...

It has been demonstrated that the oral administration of ethanol (Lieber-DeCarli liquid diet) to rats results in a decreased expression and content of the asialoglycoprotein receptor (ASGP-R) in the resultant fatty liver. In the present study, we wanted to determine whether the extent of impaired receptor content was correlated with the severity of liver pathology by using the intragastric feed...