hepatocellular carcinoma (hcc) represents one of the most common neoplasms worldwide.  liver trasnplantation (lt) is the treatment of choice for selected group of patients with hcc. lt is actually a consolidated therapeutic option for hcc because it cures both tumor and underlying cirrhosis. in 1996, the publication of a pivotal prospective study on less than 50 patients, transplanted for hcc u...

Liver Transplantation Experimental Beginnings Clinical Trials of Orthotopic Transplantation Indications for Orthotopic TransplantatIon TIssue Matching The Donor Operation The RecipIent Operation PostoperatIve Care Immunosuppression Rejection Under Immunosuppression Survival Aller Liver Replacement Causes of Mortality Steps to Reduce Mortality Opt/on of Auxiliary Liver Transplantation Potential ...

context the pnpla3 i148m variant has been recognized as a genetic determinant of liver fat content and a genetic risk factor of liver damage progression associated with steatohepatitis. the i148m variant is associated with many chronic liver diseases. however, its potential association with inflammatory and autoimmune liver diseases has not been established. evidence acquisition we systemically...

Background: Interleukin-17 (IL-17), as a potent proinflammatory cytokine, has a critical role in post liver transplant outcomes. However, there is not much information about the effects of IL-17 cytokine on acute liver rejection. Objective: To evaluate the role of IL-17 in post-liver transplant acute rejection. Methods: Ninety seven adult liver transplant patients who enrolled in this cross sec...

introduction: bone marrow transplantation is a good therapeutic modality for beta thalassemia. liver complications are one of the major causes of morbidity and mortality following bmt. determination of the factors of liver injury leads to earlier  diagnosis after bmt and improves prognosis. method: we studied 113 major beta thalassemic patients who have been transplanted from 1990- 2000 in bone...

This report describes the effect of liver transplantation on transcerebral ammonia uptake in a case of fulminant hepatic failure. A young woman with fulminant hepatic failure and coma received monitoring of transcerebral ammonia uptake before and after orthotopic liver transplantation. Before liver transplantation, median transcerebral ammonia uptake was 8 µmol/L. After liver transplantation, a...

Hepatocellular carcinoma (HCC) is the most common primary malignancy in the liver. In very early/early HCC, surgical treatment is the treatment with the best outcomes. Surgical treatment for HCC included liver resection and liver transplantation. Recently, surgical treatment is toward liver transplantation instead of liver resection because disease-free and overall survival rates are better in ...

introduction: chronic liver diseases consist of wide spectrum disorders that may be complicated by cirrhosis and therefore need to transplantation. the pediatric end-stage liver disease (peld) score and model of end-stage liver disease (meld) score has been used as predictors of mortality chronic liver diseases listed for liver transplantation. the aim of this study is evaluation of relation be...