Alopecia areata is nonscarring telogenic alopecia of autoimmune etiology. It is estimated to be the presenting complaint in 2 % of dermatologic consultations, and can appear at any age although it is more common in young patients. Treatment depends on several factors, such as extent of the disease and age, and may be local or systemic. Local treatments aim to achieve hair regrowth, but do not a...

Background: Alopecia areata (AA) is a common localized nonscarring hair loss. Vitamin D and such trace elements as zinc have significant immunomodulatory roles and are reduced in many autoimmune diseases. We aim to evaluate the zinc and vitamin D levels in AA patients belonging to an Iranian population. Methods: We randomly recruited 77 patients with AA, and 112 age- and sex-matched normal subj...

n engl j med 367;3 nejm.org july 19, 2012 279 methacin should be used in addition to pancre­ atic stents in high­risk patients. However, post hoc analysis of our trial suggests that indometha­ cin may obviate the need for prophylactic pan­ creatic stent placement (unpublished data), and we therefore agree with Baron et al. that com­ parative effectiveness studies of indomethacin and pancreatic ...

Alopecia areata is a chronic disease with a great impact on the patient's quality of life. In this study we reviewed the frequency of psychological disorders in patients with alopecia areata in comparison to a control group. We enrolled 40 patients with alopecia areata and a 40-volunteer random age-sex matched control group. The study is based on anxiety and Beck Depression Inventory (BDI) and ...

BACKGROUND Alopecia areata is a non-scarring hair loss, which typically starts quickly. Atopy is one of the possible predisposing risk factors for this condition. AIM This study aimed to evaluate the prevalence of thyroid disease, atopic dermatitis and allergic diseases in children with alopecia areata and compare the results with healthy individuals. METHODS This case-control study was con...

BACKGROUND Alopecia areata of the eyebrows can be difficult to treat. Intralesional triamcinolone or potent topical steroids are considered the mainstay of medical therapy. This case illustrates the results of an experimental hair transplant to the eyebrows following years of modest response to intralesional triamcinolone. OBJECTIVE The aim of this study was to ascertain the benefits of a hai...

Treatment of alopecia areata remains unsatisfactory. We decided to test if systemic therapy with inosiplex (Isoprinosine(R)), an immunomodulator could influence the disease. Thirty-two subjects with recalcitrant alopecia areata, aged 16-48 years (mean 30.3+/-5.1 years), were randomized into two treatment groups of 16 subjects each. They were assigned to receive either oral inosiplex (group 1), ...

conclusions our study showed that the combined use of elidel and tretinoin was more effective than elidel alone. objectives in this study, we compared the efficacy of topical elidel alone and elidel accompanied with tretinoin in the treatment of alopecia areata. patients and methods this randomized controlled clinical trial was performed on patients with alopecia areata in rasul-e akram hospita...

Protein biochips have a great potential in future parallel processing of complex samples as a research tool and in diagnostics. For the generation of protein biochips, highly automated technologies have been developed for cDNA expression library production, high throughput protein expression, large scale analysis of proteins, and protein microarray generation. Using this technology, we present ...

INTRODUCTION Alopecia areata is an autoimmune inflammatory disease affecting the hair follicles. Researchers are currently interested in whether the presence of bacterial pathogens and/or a history of immunization can trigger an autoimmune response in patients who are genetically predisposed. OBJECTIVES This study aimed to determine whether there is an association between the development of a...