نتایج جستجو برای: long noncoding rna

تعداد نتایج: 1007963  

2015
Zhonghan Li Ti-Chun Chao Kung-Yen Chang Nianwei Lin Veena S. Patil Chisato Shimizu Steven R. Head Jane C. Burns Tariq M. Rana

The long noncoding RNA THRIL regulates TNFalpha expression through its interaction with hnRNPL" (2014).

Journal: :Cell 2007
Mikel Zaratiegui Danielle V. Irvine Robert A. Martienssen

Noncoding RNA has long been proposed to control gene expression via sequence-specific interactions with regulatory regions. Here, we review the role of noncoding RNA in heterochromatic silencing and in the silencing of transposable elements (TEs), unpaired DNA in meiosis, and developmentally excised DNA. The role of cotranscriptional processing by RNA interference and by other mechanisms is dis...

Journal: :Investigative Opthalmology & Visual Science 2017

Journal: :Cell 2008
Jeremy E. Wilusz Susan M. Freier David L. Spector

MALAT1 is a long noncoding RNA known to be misregulated in many human cancers. We have identified a highly conserved small RNA of 61 nucleotides originating from the MALAT1 locus that is broadly expressed in human tissues. Although the long MALAT1 transcript localizes to nuclear speckles, the small RNA is found exclusively in the cytoplasm. RNase P cleaves the nascent MALAT1 transcript downstre...

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