introduction: verapamil, a phenylalkylamin –type ca2+ channel blocker, is widely used in the treatment of cardiovascular disorders especially as an antiaryhthmic and antiangina agent. theoretically, calcium can influence thyroid function and there are evidences that ca2+ channel blockers are able to interfere with thyroid function. in this study, the effects of chronic oral administration of ve...

The long-term hydrothermal scheduling (LTHS) problem seeks to obtain an operational policy that optimizes water resource management. most employed strategy such a is stochastic dual dynamic programming (SDDP). primary source of uncertainty in predominant hydropower systems the reservoirs inflow, usually linear time series model (TSM) based on order-p periodic autoregressive [PAR(p)] model. Alth...

scheduling is an important subject of production and operations management area. in flow-shop scheduling, the objective is to obtain a sequence of jobs which when processed in a fixed order of machines, will optimize some well defined criteria. the concept of transportation time is very important in scheduling. transportation can be done by robots. in situations that robots are used to transpor...

We consider several scheduling problems for packet based systems with time-varying channel conditions. Designing scheduling mechanisms that take advantage of time-varying channel conditions, which are different for different users, is necessary to improve system performance; however this has to be done in a way that provides some level of fairness among the users. Such scheduling mechanisms are...

The mine production planning defines a sequence of block extraction to obtain the highest NPV under a number of constraints. Mathematical programming has become a widespread approach to optimize production planning, for open pit mines since the 1960s. However, the previous and existing models are found to be limited in their ability to explicitly incorporate the ore grade uncertainty into the p...