We have created a large longitudinal research cohort, SPARK (SPARKForAutism.org) to advance on the genetic, behavioral, and clinical features associated with ASD. represents largest ASD cohort in world, over 100,000 individuals enrolled. Despite known heritable nature of autism spectrum disorder (ASD), studies primarily identified risk genes de novo variants (DNVs).

To draw valid inferences regarding growth parameters from accelerated longitudinal or cohortsequential designs requires no cohort differences among the cohort-specific trajectories. Conventional structural equation modeling (SEM) fit indices have been regularly used to imply the existence of a common trajectory across cohorts. We argue that adequate fit implied by these SEM indices may indicate...

BACKGROUND Whilst many studies have analysed predictors of longitudinal cognitive decline, few have described their impact on population distributions of cognition by age cohort. The aim of this paper was to examine whether gender, education, social class and birth cohort affect how mean population cognition changes with age. METHODS The Medical Research Council Cognitive Function and Ageing ...

Background: Gastric cancer (GC) is one of the most common Cancers in the world and Helicobacter pylori (HP) infection is considered a causative factor. The aim of this study was to determine the characteristics and the associated factors of (GC) in a small cohort. Methods: Overall, 54 patients with diagnosed gastric cancer were followed-up at the Department of Gastroenterology & Hepatology a...

PURPOSE More research into the psychosocial aspects of diabetes is needed so that the health and quality of life of people with the condition can be improved. To fill this gap, we conducted the second Diabetes MILES-Australia study (MILES-2), a survey focused on psychological, behavioural and social aspects of diabetes. The aim of the MILES-2 study was to provide a (1) longitudinal follow-up of...