BACKGROUND In genetic research on essential tremor (ET), certain individuals may be particularly challenging to categorize diagnostically. METHODS In the Family Study of Essential Tremor (>200 enrollees), 28 participants with borderline clinical findings who did not meet strict criteria for ET were assigned final diagnoses of ET. We scrutinized the clinical features of these cases and the sen...

Lot-sizing and capacity planning are important supply chain decisions, and competition and cooperation affect the performance of these decisions. In this paper, we look into the dynamic lot sizing and resource competition problem of an industry consisting of multiple firms. A capacity competition model combining the complexity of time-varying demand with cost functions and economies os scale ar...

Despite considerable progress within wilderness and adventure therapy research over the last decade, researchers are still unable to precisely answer why, how, and for whom this treatment modality works. There is also a need for more knowledge regarding the circumstances under which the treatment does not appear to be effective. In this realist synthesis, we attempt to unpack this "black box" o...

Patient-physician interactions are increasingly influenced by the extraordinary diversification of populations and rapid expansion of medical knowledge that characterize our modern era. By contrast, the patient-physician interaction models currently used to teach medical trainees have little capacity to address these twin challenges. We developed a new model of patient-physician interaction to ...

Supply network issues recently have attracted a lot of attention from industrial practitioners and academics worldwide. Supply networks are highly complex systems. The oscillations in demand and inventory as orders pass through the system have been widely studied in literature. Studies have shown that supply networks can display some of the key characteristics of chaotic systems. Chaos theory i...