نتایج جستجو برای: low dose interferon

تعداد نتایج: 1503914  

Journal: :The New England journal of medicine 1986
J H Hoofnagle K D Mullen D B Jones V Rustgi A Di Bisceglie M Peters J G Waggoner Y Park E A Jones

We treated 10 patients who had chronic non-A,non-B hepatitis with recombinant human alpha interferon in varying doses (0.5 to 5 million units) daily, every other day, or three times weekly for up to 12 months. In 8 of the 10 patients, elevated serum aminotransferase levels decreased rapidly during therapy and eventually fell into the normal or nearly normal range. In two of these patients, the ...

Journal: :Dose-response : a publication of International Hormesis Society 2006
Shu-Zheng Liu

Previous studies showed that low dose radiation (LDR) could stimulate the immune system in both animal and human populations. This paper reviews the present status of relevant research as support to the use of LDR in clinical practice for cancer prevention and treatment. It has been demonstrated that radiation-induced changes in immune activity follows an inverse J-shaped curve, i.e., low dose ...

Journal: :Arquivos de neuro-psiquiatria 2002
Marco Aurélio Lana-Peixoto Antônio Lúcio Teixeira Vitor Geraldi Haase

Depression and suicide have been reported in association with multiple sclerosis (MS). Some studies show that interferon beta may increase the depression rate. We report a case of depression and suicidal ideation in coincidence with the start of increased doses of interferon beta-1a and their complete reversal following the drug withdrawal. The patient was a 21-year-old man with MS and no past ...

Journal: :Journal of clinical and experimental hematopathology : JCEH 2006
Yusuke Saito Yoshiki Yanagawa Kazuhiro Kikuchi Norifumi Iijima Kazuya Iwabuchi Kazunori Onoé

Dendritic cell (DC) activation is triggered by cytokines, including tumor necrosis factor (TNF)-alpha, and microbe components, including lipopolysaccharide (LPS). During the initial stage of infection, the microbe components appear to be present at low concentration. To determine the role of low-dose microbe-components in DC activation during the initial stage of infection, we examined the effe...

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