BACKGROUND Excess consumption of energy-dense, high-fat Western diets contributes to the development of obesity and obesity-related disorders, such as fatty liver disease. However, not only the quantity but also the composition of dietary fat may play a role in the development of liver steatosis. The aim of this study was to determine the effects of low-stearate palm oil and high-stearate lard ...

We investigated the effects of piroxicam, a cyclooxygenase inhibitor, and esculetin, a lipoxygenase inhibitor, on 7,12-dimethylbenz[a]anthracene (DMBA)-induced mammary carcinogenesis in female rats. Seven days after receiving a 5-mg dose of DMBA, rats were fed either a high-fat (20% soybean oil) or low-fat (0.5% soybean oil) diet. One third of the rats received diets containing 0.01% piroxicam ...

OBJECTIVE To assess the effects of dietary modifications on oxidized low-density lipoprotein (LDL). METHODS AND RESULTS Thirty-seven healthy women were fed two diets. Both diets contained a reduced amount of total and saturated fat. In addition, one diet was low in vegetables and the other was high in vegetables, berries, and fruit. The dietary intake of total fat was 70 g per day at baseline...

The typical American diet derives 37% of total daily energy intake from fat.' Fat consumption in the U.S. has been estimated at 98 g/day for men and 65 g/day for women.' Diets low in carbohydrate and fiber but rich in fat have been associated with high prevalence of obesity and elevated risks of coronary artery disease and some forms of cancer.233 Current nutritional guidelines recommend reduci...

Recently high-carbohydrate, low-fat diets have been widely advocated for diabetic patients (3, 17, 20, 23, 24, 30, 36, 48, 52). As arguments for this therapy it has been claimed that hypercholesterolemia is of grave prognosis in diabetes and that high fat diets may superinduce hyperlipemia. The following investigation was undertaken to determine the incidence of hypercholesterolemia in diabetes...

BACKGROUND Nuts appear to have cardiovascular benefits but their effect in diabetic patients is unclear. OBJECTIVE The objective was to assess effects of almond-enriched diets on insulin sensitivity and lipids in patients with normoglycemia or type 2 diabetes. DESIGN Study 1 assessed the effect of almonds on insulin sensitivity in 20 free-living healthy volunteers who received 100 g almonds...

Frailty is a major health issue associated with aging. Diet affects frailty status; however, studies on the associations between low-carbohydrate diet (LCD) score, low-fat (LFD) score and in older Chinese adults are scarce. This study aimed to examine LCD LFD risk of adults. We analyzed data from 6414 participants aged ≥ 60 years China Northwest Natural Population Cohort: Ningxia Project. was m...

BACKGROUND Relatively little is known about the role of specific saturated fatty acids in the development of high fat diet induced obesity and insulin resistance. Here, we have studied the effect of stearate in high fat diets (45% energy as fat) on whole body energy metabolism and tissue specific insulin sensitivity. METHODS C57Bl/6 mice were fed a low stearate diet based on palm oil or one o...

the hypothesis of this experiment was that the various sources of dietary fat with different dietary ratios of polyunsaturated fatty acids (pufas) to saturated fatty acids (sfas) would alter the reproduction parameters of mature rams. twelve mature rams were randomly allotted to one of four dietary treatments in a completely randomized design. dietary treatments were: 1) ration with 4% soybean ...

BACKGROUND Little evidence of the effects of moderate-fat (from monounsaturated fat) weight-loss diets on risk factors for cardiovascular disease exists because low-fat diets are typically recommended. Previous studies in weight-stable persons showed that a moderate-fat diet results in a more favorable lipid and lipoprotein profile (ie, lower serum triacylglycerol and higher HDL cholesterol) th...