The antimicrobial activity of five sanitizing agents employed in clean areas designated for the pharmaceutical manufacturing of sterile products was tested against nine microorganisms, including four microorganisms from the clean area microbiota. The method consisted of challenging 5 mL of each sanitizing agent 70% isopropyl alcohol, 0.4% LPH®, 1.16% hydrogen peroxide, 4% hydrogen peroxide, 1% ...

The activation of the hypothalamic pituitary adrenal axis by stress is well-known. Using inescapable intermittent footshock as a stressor in rats, we have previously demonstrated a rise in circulating plasma Beta-endorphin/Beta-LPH which parallels the rise in plasma ACTH, the primary POMC derived peptides released by anterior lobe. In addition, the rise in ACTH is accompanied by approximately a...

The electrocardiogram in 480 patients with acute myocardial infarction showed right bundle-branch block (RBBB) with normal QRS axis in 18 patients (3.7%), left bundle-branch block (LBBB) in 31 (8%), RBBB and left anterior hemiblock (LAH) in 23 (4.8%), RBBB and left posterior hemiblock (LPH) in four (1%), LAH alone in 20 (4%), LPH in one (0.2%), and no evidence of intraventricular conduction (I-...

The focus of research in our laboratory over the past few years has been the regulation of synthesis, processing and release of the ACTH/LPH family of peptides. These peptides are derived from a common precursor protein that is found in both the anterior and intermediate lobes of the pituitary (Roberts et al. 1978) and in the hypothalamus (Liotta et al. 1979). In the anterior lobe this protein ...

We report here the extremely rare case of a twenty-eight year-old woman with a metastatic ACTH-secreting pituitary carcinoma. This is the thirteenth case to be described in the literature. Ten years ago Cushing's disease was diagnosed. After pituitary surgery, then bilateral adrenalectomy, a Nelson's syndrome appeared. The particularly extensive pituitary secondary development led to several pi...

@‘‡rqrqÃ6i†‡…hp‡ The focus of this work involves the investigation of parallelization and performance improvement for a class of radar signal processing techniques known as space-time adaptive processing (STAP). STAP refers to an extension of adaptive antenna signal processing methods that operate on a set of radar returns gathered from multiple elements of an antenna array over a specified ti...

Stroke variably activates interleukin- (IL-) 17 expression, reduces regulatory T cells, and induces oxidative stress, which may support neurodegeneration. Ischemic stroke patients were screened for depressive symptoms (Center for Epidemiological Studies Depression (CES-D)) and cognitive status (Mini Mental State Examination). Proinflammatory cytokines (IL-17, IL-23, and interferon- [IFN-] γ), a...

Objectives The assessment of oxidative stress (OS) in serum relapsing-remitting multiple sclerosis patients treated with II-line immunomodulatory therapy (fingolimod, natalizumab) compared to newly diagnosed patients (de novo group) treated with interferon (IFN) beta and controls. The relationship between OS parameters and gender, age, disease duration, Expanded Disability Status Scale, annuali...

The electrocardiogram in 480 patients with acute myocardial infarction showed right bundle-branch block (RBBB) with normal QRS axis in 18 patients (3.7%), left bundle-branch block (LBBB) in 31 (8%), RBBB and left anterior hemiblock (LAH) in 23 (4.8%), RBBB and left posterior hemiblock (LPH) in four (1%), LAH alone in 20 (4%), LPH in one (0.2%), and no evidence of intraventricular conduction (I-...

The present study was designed to explore the possible influence of subacute exposure to lead on the levels of selected essential metals, selected proteins related to them, and oxidative stress parameters in occupationally exposed workers. The study population included 36 males occupationally exposed to lead for 36 to 44 days. Their blood lead level at the beginning of the study was 10.7 ± 7.67...