PURPOSE To determine the risk of second malignancies after lumpectomy and radiation therapy (LRT), and to compare it with that in a similar cohort of early-stage breast cancer patients undergoing mastectomy without radiation (MAST). PATIENTS AND METHODS Between January 1970 and December 1990, 1,029 breast cancer patients at our institution underwent LRT. A cohort of 1,387 breast cancer patien...

The FTA has identified the concept of Bus Rapid Transit as a means to increase the efficiency of transit operations while maintaining transit's proven safety record. According to the FTA website www.fta.dot.gov, " BRT combines the quality of rail transit and the flexibility of buses. It can operate on exclusive transitways, HOV lanes, expressways, or ordinary streets. A BRT system combines inte...

Multivariate one-sided hypothesis-testing problems are very common in clinical trials with multiple endpoints. The likelihood ratio test (LRT) and union-intersection test (UIT) are widely used for testing such problems. It is argued that, for many important multivariate one-sided testing problems, the LRT and UIT fail to adapt to the presence of subregions of varying dimensionalities on the bou...

Recently, there have been many case-control studies proposed to test for association between haplotypes and disease, which require the Hardy-Weinberg equilibrium (HWE) assumption of haplotype frequencies. As such, haplotype inference of unphased genotypes and development of haplotype-based HWE tests are crucial prior to fine mapping. The goodness-of-fit test is a frequently-used method to test ...

Split liver transplantation (SLT) and living related transplantation (LRT) have been developed following advancements in liver surgery. In experienced hands they can yield results comparable to full organ liver transplantation. They are today a reality which has to be implemented and used more widely. LRT is the best procedure available and should be the method of choice despite the high succes...

We study the possibility of testing local realistic theory (LRT), envisioned implicitly by Einstein, Podolsky and Rosen in 1935, based on the Bell inequality for the correlations in the decay modes of entangled K or B-mesons. It is shown that such a test is possible for a restricted class of LRT, despite the passive nature of decay events and/or the non-unitary treatment of the correlations whi...

The influence of low-frequency electromagnetic (LF-EM) waves on microorganisms has been a subject of experimental investigations for more than two decades and the results are promising. In parallel, an interesting procedure known as biophysical-information-therapy or bioresonance therapy (BRT) which in principle is based on LF-EM stimulation, has emerged. BRT was discovered in the late 1980's b...

The flexibility of bus rapid transit (BRT) in scheduling is one of the greatest differences with traditional buses. In order to improve BRT operation quality, the paper studied the headway optimization and scheduling combination of BRT vehicles. A model has been established to minimize passengers’ travel costs and vehicles’ operation cost, and constraints included passenger volume, time, and fr...

BACKGROUND The built environment can constrain or facilitate physical activity. Most studies of the health consequences of the built environment face problems of selection bias associated with confounding effects of residential choice and transportation decisions. PURPOSE To examine the cross-sectional associations between objective and perceived measures of the built environment; BMI; obesit...