Introduction: Accelerated Partial Breast Irradiation (APBI) is an effective treatment for breast carcinomas because of its limited number of fractions. Strut-adjusted volume implant (SAVI) is a HDR brachytherapy applicator to deliver the prescription dose with good PTV coverage and acceptable dose to skin, chest wall and organ at risks. Acceptable clinical outcomes depend on a...

Purpose To present the implementation of a magnetic resonance imaging (MRI) pre-planning technique in multi-interstitial perineal and endocavitary gynecological brachytherapy. Material and methods We used a new fully MRI-compatible applicator that is capable to engage titanium needles, and an intrauterine tandem, developed in our department for the treatment of gynecological cervical cancer p...

PURPOSE The Strut-Adjusted Volume Implant (SAVI; Cianna Medical, Aliso Viejo, CA) is a multichannel single-entry brachytherapy device designed to allow dose modulation to minimize normal tissue dose while simultaneously maximizing target coverage. This is the first report on the initial 102 patients with nearly 2 years of median follow-up. METHODS AND MATERIALS One hundred two patients were t...

Cryotherapy, brachytherapy and photodynamic therapy (PDT) are three different methods proposed in the endoluminal treatment of lung cancers. The current article presents an overview of the specific indications and limits of each technique. These three methods were first proposed with palliative intent in inoperable patients with centrally located lung cancers. Now, the best indication is a cura...

Purpose To evaluate the correlations of post-implant regional dosimetrics at 24 hours (24 h) and 1 month after implant procedures, with clinical outcomes of low-dose-rate (LDR) brachytherapy for localized prostate cancer. Material and methods Between January 2008 and December 2014, 130 consecutive patients treated for localized prostate cancer, receiving definitive iodine-125 (125I) brachythe...

PURPOSE To develop an accurate method of fusing computed tomography (CT) with magnetic resonance imaging (MRI) for post-implant dosimetry after prostate seed implant brachytherapy. MATERIAL AND METHODS Prostate cancer patients were scheduled to undergo CT and MRI after brachytherapy. We obtained the three MRI sequences on fat-suppressed T1-weighted imaging (FST1-WI), T2-weighted imaging (T2-W...

PURPOSE To evaluate prostate-cancer specific mortality (PCSM) in a cohort of high-risk patients treated with a permanent prostate brachytherapy approach, stratified by pre-treatment PSA. MATERIAL AND METHODS 448 high-risk patients (NCCN criteria) underwent permanent prostate brachytherapy. High risk patients were stratified by pre-treatment PSA (≤ 10.0, 10.1-20, and > 20 ng/ml). Biochemical f...

PURPOSE To evaluate biochemical failure (BF) and prostate cancer specific mortality (PCSM) in intermediate-risk (IR) brachytherapy patients stratified into favorable and unfavorable cohorts, and to compare those outcomes to patients with low (LR) and high-risk (HR) disease. MATERIAL AND METHODS From March 1995 till February 2012, 2,502 consecutive patients underwent permanent interstitial bra...

PURPOSE In radiotherapy treatment planning, dose homogeneity inside the target volume plays a significant role in the final treatment outcome. Especially in brachytherapy where there is a steep dose gradient in the dose distribution inside the target volume, comparing the plans based on the dose homogeneity helps in assessing the high dose volume inside the final treatment plan. In brachytherap...

In March 2004, the recommendations of the American Association of Physicists in Medicine sAAPMd on the interstitial brachytherapy dosimetry using I and Pd were reported in Medical Physics fTG-43 Update: Rivard et al., 31, 633–674 s2004dg. These recommendations include some minor changes in the dose-calculation formalism and a major update of the dosimetry parameters for eight widely used inters...