BACKGROUND Cardiac disorders are very common in individuals with chronic kidney disease and are associated with morbimortality. OBJECTIVE To evaluate cardiac alterations after kidney transplantation. METHODS We prospectively evaluated 40 patients with chronic kidney disease, immediately before and one month, three months and six months after kidney transplantation, using tissue Doppler echo...

Primary aldosteronism is a common form of secondary hypertension that is associated with a variety of cardiovascular sequelae. Studies conducted in patients with this endocrine disorder have consistently reported greater frequency of cardiovascular events than in well-matched patients with primary hypertension. Subclinical cardiac changes that forego cardiovascular events in patients with hyper...

One mechanism linking diet, specifically the Mediterranean-style diet (DT), with cardiovascular disease prevention may be an association between a DT and left ventricular (LV) mass. However, there are little data on this relation. We hypothesized that adherence to a DT would be inversely associated with LV mass in the multiethnic population-based Northern Manhattan Study. The study included 1,9...

BACKGROUND Tagged cardiac magnetic resonance provides detailed information on regional myocardial function and mechanical behavior. T1 mapping by cardiac magnetic resonance allows noninvasive quantification of myocardial extracellular expansion (ECE), which has been related to interstitial fibrosis in previous clinical and subclinical studies. We assessed sex-associated differences in the relat...

CONTEXT Adiponectin inhibits protein synthesis in cardiac myocytes, thereby opposing the effect of cardiac workload and trophic factors (in particular, insulin) on left ventricular (LV) mass and wall thickness (WT). OBJECTIVE We tested whether adiponectin and its isoforms are related to LV mass, WT, and function independently of metabolic factors. DESIGN This was a cross-sectional study. ...

Metabolic syndrome (MS) is increasingly recognized as an important cardiovascular risk factor in hypertension, but its influence on left ventricular (LV) mass and function in the 2 genders has not been specifically addressed. Among 618 nondiabetic, untreated hypertensive subjects, echocardiographically detected LV mass was significantly greater in subjects with MS. A significant interaction was...

Seventeen patients, ages 14-74 years, with severe, isolated aortic insufficiency and reduced ejection fraction (0.25-0.49) underwent aortic valve replacement between January 1973 and July 1977. Three had coronary artery disease and also underwent coronary bypass surgery. By New York Heart Association criteria, one patient was functional class IV, seven were class III, seven were class II and tw...

OBJECTIVE To assess the impact of obesity on carotid intima media thickness and left ventricular (LV) mass in obese adolescents. METHODS The study included 52 obese adolescents (mean age 14.16+/-2.64 years) and 52 healthy adolescents who served as a control group (mean age 12+/-2.3 years), who were attended the outpatient clinic at Suez Canal University Hospital, Ismailia, Egypt. The study po...

OBJECTIVE Heart failure is common in individuals with type 2 diabetes, and early detection of individuals at risk may offer opportunities for prevention. We aimed to explore 1) prospective associations of B-type natriuretic peptide (BNP) levels in a non-heart failure range with changes in markers of left ventricular (LV) function and 2) possible effect modification by type 2 diabetes in a popul...

AIM The cardio-ankle vascular index (CAVI) has been proposed as a new noninvasive marker of arterial stiffness independent of blood pressure. We investigated the association of the CAVI with coronary atherosclerosis and left ventricular (LV) systolic and diastolic function in patients with ischemic heart disease (IHD). METHODS A total of 206 consecutive subjects undergoing coronary angiograph...