Prominent and localized lymphoid hyperplasia in the rectum is also known as rectal tonsil (RT) [1, 2]. When the reactive lymphoid infiltrate is very exuberant with atypical lymphoid cells it can be difficult to distinguish from lymphoma on histology [3]. To avoid overdiagnosis and overtreatment, immunophenotypic and genotypic studies are necessary [3–5]. A 4-year-old girl, without relevant medi...

BACKGROUND Pseudolymphomatous folliculitis is a lymphoid proliferation that clinically and histopathologically mimics primary cutaneous extranodal marginal zone lymphoma of mucosa-associated lymphoid tissue (MALT lymphoma). In this study, we assessed the diagnostic value of three immunohistochemical markers, programmed death-1 (PD-1), CD1a and S100. METHODS We evaluated 25 cases of cutaneous ...

The lymphoid stromal reaction, particularly the T lymphoid reaction, was studied immunohistochemically on cryostat sections in 14 cases of primary gastrointestinal B lymphomas, and compared with the type and distribution of lymphoid cells in three cases of gastric lymphoid hyperplasia. A pronounced T lymphoid reaction, mainly of the T helper phenotype, occurred in both lesions. Most of these T ...

We report the case of a patient who presented with cystic lymphoid hyperplasia of the right parotid gland as the index diagnosis of HIV infection. Histological examination of the excised parotid gland revealed a solid-cystic lymphoepithelial lesion with a non-keratinous squamous epithelium, which grew into the lymphoid component via anastomosing cords and islands. These anastomosing cords and i...

Objective: To compare computed tomographic (CT) appearance of the thymus with results from histologic examination of thymic tissue and clinical outcome in patients with myasthenia gravis who underwent thymectomy with or without plasmapheresis. Method and Materials: This study comprised of 47 patients, who were operated on in the period from January 2002 to December 2009 for myasthenia gravis. C...

Extra nodal marginal zone B-cell lymphoma (EMZL) of the conjunctiva typically arises in the marginal zone of mucosa-associated lymphoid tissue. The pathogenesis of conjunctival EMZL remains unknown. We describe an unusual case of EMZL arising from reactive lymphoid hyperplasia (RLH) of the conjunctiva. A 35-year-old woman had fleshy salmon-pink conjunctival tumors in both eyes, oculus uterque (...

Reactive lymphoid hyperplasia (RLH) is a rare benign condition that forms a mass-like lesion characterized by proliferation of nonneoplastic lymphocytes forming follicles and germinal centers. RLH is thought to represent a reactive immunological response, and some cases may arise in association with malignancy and hepatitis. Radiologically, RLH of the liver may mimic a primary or metastatic hep...

Clinical features of giardiasis vary greatly between individuals and may range from asymptomatic infection to severe malab− sorption syndrome. Whereas individuals with various forms of hypogammaglobu− linemia may show more severe disease and damage to the intestinal villi, AIDS patients do not appear to be at increased risk of severe giardiasis [1]. We present a case of duodenal giardiasis in a...