Posttransplant lymphoproliferative disorder is a serious complication following solid organ as well as hematopoietic stem cell transplantation due to prolonged immunosuppressive therapy. Plasmablastic lymphoma, although classically associated with HIV infection, has since been described in transplant patients as a variant of posttransplant lymphoproliferative disorder with varying clinical pres...

Hematologic malignancies and lymphoproliferative disorders have been reported after using tumor necrosis factor-α inhibitor in patients suffering from spondyloarthropathy. Previously reported cases were treated by using infliximab and etanercept. Usually, it takes approximately several months for leukemia or lymphoproliferative disorders to occur after the application of those agents. However, ...

The paper reported on a case of severe myoclonic epilepsy of infancy (SMEI) associated with a probable autoimmune lymphoproliferative syndrome variant (Dianzani autoimmune lymphoproliferative disease) (DALD). A male patient with typical features of SMEI and a SCN1A gene variant presented in the first year of life with multiple lymph nodes, palpable liver at 2 cm from the costal margin, neutrope...

B cell non-Hodgkin lymphoma is a typical extrahepatic manifestation frequently associated with hepatitis C virus (HCV) infection. The mechanism by which HCV infection leads to lymphoproliferative disorder remains unclear. Our group established HCV transgenic mice that expressed the full HCV genome in B cells (RzCD19Cre mice). We observed a 25.0% incidence of diffuse large B cell non-Hodgkin lym...

a patient with malignant lymphoma who developed rheumatoid arthritis and facial edema resembling scleredema of buschke is described. pifall s in the clinical diagnosis of this unusual event are stressed. a possiblerelationship between diseases is considered. lymphosarcoma ... immunological disorders and lymphoproliferative disease is considreved

Pagetoid reticulosis (PR) is a low-grade primary cutaneous T-cell lymphoma that usually presents as a solitary, slowly enlarging erythematous or hyperkeratotic plaque on the distal areas of the extremities. Histopathologically, it is characterized by a dense, band-like infiltrate of atypical lymphocytes with prominent epidermotropism within a hyperplastic epidermis, and immunophenotypic studies...

Signal Transducer and Activator of Transcription 6 (STAT6) is critical for IL-4 and IL-13 responses, and necessary for the normal development of Th2 cells. We previously generated mice that express a constitutively active STAT6 (STAT6VT) under control of the CD2 locus control region, which directs expression to the T cell compartment. We now describe that a small proportion of these mice (~5%) ...

The in vitro lymphoproliferative responses to herpes simplex virus (HSV) antigens were followed in rabbits with herpesvirus infection of the cornea. The proliferative cellular responses occurred early in infection and were demonstrated by lymphoid cells from the local lymph nodes at day 5, the peripheral blood at day 11, and the spleen after day 14. The presence of autologous serum antibodies s...

Post-transplant lymphoproliferative disorder complicates approximately 1% of all renal transplants. The usual site of occurrence is within the abdomen, thorax, allograft, or head and neck. Central nervous system involvement is uncommon but, when present, occurs in isolation, sparing other organ systems. Few articles in the radiology literature have focused on the acute and follow-up central ner...