A new six coordinated tetra-nuclear macrocyclic Zn(II) complex, ZnL4(Phen)2 (1) (HL= 3-bromo-2-hydroxybenzaldehyde-pyridine-2-carbohydrazone, Phen = 1,10-phenanthroline) has been synthesized by the self-assembly of Zn(CH3COO)2•2H2O, NaOH and 1,10-phenanthroline in water/ethanol (v:v 1:3) solution. Complex 1 was characterized elemental analysis, infra red (IR), single-crystal X-ray diffraction (...

Phosphorus-based Mannich-type reactions (phospha-Mannich reactions) of primary or secondary phosphines with carbonyl compounds and amines (R2NH, RNH2, NH3) provide a powerful synthetic tool in the worldwide search for future ligands. The variety available allows designing fine-tuning water-soluble, chiral, macrocyclic, pincer, tripodal, photoactive, etc., phosphine ligands P–C–N linkage(s) (P,N...

Present study shows the Rationale behind the synthesis of chelating agents and their thermodynamic stability along with kinetic inertness of metal complex in vivo is the prerequisites for the successful application of bifunctional chelating agentconjugate. Macrocyclic bifunctional chelating agents (BFCs) with their established stabilizing properties are in the forefront for radio-immuno applica...

( * ) Notice: Subject to any disclaimer, the term of this W0 WO 91/10645 7/1991 patent is extended or adjusted under 35 W0 WO 92/08707 5/1992 U'S'C~ 154(1)) by 0 days' W0 WO 92/21017 11/1992 W0 WO 93/05049 3/1993 (21) Appl. N0.: 10/737,486 W0 WO 93/06868 4/1993 W0 WO 93/12097 6/1993 (22) Filed: Dec. 16, 2003 W0 WO 93/14093 7/1993 W0 WO 94/15925 7/1994 (65) Prior Publication Data W0 WO 94/26315 ...

An aqueous self-assembled micellar system (sodium dodecyl sulfate, SDS, decorated with various adhesive sites, cryptand Kryptofix 222 and crown ether 18-Crown-6 molecules) has been investigated by dynamic light scattering (DLS) and small angle x-ray scattering (SAXS) to have insights into the micellar structure, the micellar interactions, and the aggregation properties of the system. DLS demons...

Macrocyclic scaffolds are particularly attractive for designing selective G-quadruplex ligands essentially because, on one hand, they show a poor affinity for the "standard" B-DNA conformation and, on the other hand, they fit nicely with the external G-quartets of quadruplexes. Stimulated by the pioneering studies on the cationic porphyrin TMPyP4 and the natural product telomestatin, follow-up ...

Oxovanadium(IV) complexes of the type [VO(mac)]SO4 , (where mac = tetraaza macrocyclic ligands derived by condensation of furil with 1,4-diaminobenzene or 3,4-diaminopyridine and their reaction with βdiketones) have been prepared using vanadyl ion as kinetic template. Tentative structures of the complexes have been proposed on the basis of elemental analysis, infrared, e.s.r. and electronic dat...

The reaction of tetrakis[bis(trimethylsilyl)methyl]digallane(4), 1, with 1,1′-ferrocenedicarboxylic acid afforded orange-red crystals of the macrocyclic compound 2 in a yield of 84%. 2 contains a large 32-atom heterocycle, which comprises four Ga-Ga single bonds bridged by four 1,1′-ferrocenedicarboxylato ligands. The largest diameter of the molecule is about 2.5 nm. The redox-active Ga-Ga site...

This paper deals with the synthesis and characterization of macrocyclic ligand and its complex compound. Template condensation of chlorocarbons such as 1,1,2,2-tetrachloroethane with 1,3-diaminopropane in presence of nickel (II) or copper (II) yielded the corresponding metal complexes such as 3,7,10,14,15,19,20,24octaazatricyclotetracosane (OCTC). The macrocyclic ligands and their complexes hav...